Am  jJa°nU,r"i8P78f rm  }         Fluid  Extract  of  Cimicifuga.  1 3 
finally  added  until  the  desired  amount  of  percolate  was  obtained.  This 
was  divided  as  it  came  into  three  portions,  7J,  and  \\  fluidounces. 
The  first,  7J,  was  reserved. 
3,840  grains  of  powdered  cimicifuga  were  moistened  with  2  fluid- 
ounces  of  the  second  percolate  obtained  in  the  preceding  operation  ; 
pressed  into  a  three  inch  percolator  until  it  occupied  five  inches  in 
height.  The  remainder  of  the  \\  fluidounces  of  percolate  was  added, 
allowed  to  disappear,  followed  with  the  last  percolate,  4^f§,  and  then 
at  once  with  alcohol.  Ten  and  a  half  fluidounces  of  percolate  were 
obtained  ;  this  and  the  two  reserved  percolates  were  mixed  together, 
representing  24  fluidounces  of  the  fluid  extract  of  cimicifuga  made  by 
the  repercolation  process.    Table  No.  6  shows  the  result. 
Simple  Percolation. — 24  troyounces  of  powdered  cimicifuga  were 
moistened  with  6  fluidounces  of  alcohol,  and  pressed  into  a  three  inch 
cylindrical  percolator  until  it  occupied  15  inches  in  height.  After 
being  covered  with  a  circular  piece  of  filter  paper,  60  fluidounces  of 
alcohol  were  added  and  percolation  continued  until  24  fluidounces  of 
percolate  were  obtained  \  this  was  reserved  in  three  fractions  to  corres- 
pond with  the  three  reserved  percolates  of  the  repercolation  proccess. 
Table  No.  7  places  the  result  where  the  two  processes  can  be  compared. 
TABLE  7.  Result  of  Experiments  by  Percolation. 
0 
O  «  u 
a!  cu 
p- 
**  E 
16  floz.  of  finished  fluid  extract 
Amount  of  powder 
0 
-0  c 
0  V  . 
hi 
operated  upon. 
a  . 
*j  >  u 
represent  powd'd 
§3 
in  1  cc. 
m 
Cimicifuga. 
< 
< 
H 
24  02.  powder 
io-5  f3 
r96gr. 
607-52  grs. 
The  same  powder 
7'5 
r38 
305-55 
The  same  powder 
6 
•93 
164*72 
24- 
107779 
718-51  grs. 
4869-28  grs. 
Recapitulation. — The  total  amount  of  extractive  matter  obtained  by- 
the  repercolation  process  was  973*28  grains,  by  simple  percolation  1077*- 
79,  being  an  excess  in  favor  of  simple  percolation  of  104*51  grains, 
which  represented  708*25  grains  of  cimicifuga.  Sixteen  fluidounces  of 
the  finished  fluid  extract  represented  near  9  troyounces  of  cimicifuga 
