Am.  Jour.  Pharm. 
April,  1878. 
Distinction  of  the  Cinchona  Alkaloids. 
19 
by  Merk  of  Darmstadt.  Of  each  a  saturated  aqueous  solution  was 
made,  and  filtered  only  when  needed  for  the  microscopic  examination. 
When  a  drop  of  the  filtrate  is  placed  upon  a  glass  slide  and  mixed  with 
a  drop  of  the  solution  of  potassium  sulphocyanide  a  white  turbidity  is 
at  once  produced,  which  is  faintest  when  quinia  sulphate  is  used. 
Examined  under  the  microscope  with  a  magnifying  power  of  110 
diameters,  the  following  is  observed  : 
Fig.  1.  Quinia  Sulphate  with  KScy. 
Quinia  sulphate. 
I.  Ghiinia  Sulphate. — Small  globules  or  round  vesicles,  which  even 
after  a  day  do  not  unite  and  form  neither  groups  nor  crystals  (Fig.  1). 
Schrage  described  stellate  groups  of  thin  needles  or  spikes,  which  were 
also  observed  by  the  authors  when  working  after  Schrage's  directions, 
but  only  in  that  portion  of  the  liquid  which  had  not  become  milky, 
Fig-  3.  Quinidia  sulphate  with  KScy. 
Fig.  4.  Cinchonia  sulphate  with  KScy. 
while  the  latter  contained  only  the  described  globules  or  vesicles.  The 
stellate  groups  (Fig.  2)  were,  by  comparison,  recognized  as  quinia  sul- 
