Advertising  Sheet  of  the  American  Journal  of  Pharmacy. 
October,  [Terms  on  the  Cover.]  1878 
THE  BEST  IN  THE  MARKET. 
PARKE,  DAVIS  *  CO.'S 
ZMFRO  XTJSiJD 
EMPTY  CAPSULES. 
Our  Capsules  are  manufactured  by  means  of  improved  apparatus,  producing  the 
most  accurate  and  unvarying  results.     The  gelatine   employed  is  of  the 
finest  quality,  which,  in  our  hands,  undergoes  a  certain  process,  increasing 
its  transparency  and  elasticity.    Through  these  improvements  in  appa- 
ratus and  material,  we  are  enabled  to  produce  capsules  which  are 
uniformly  accurate,  transparent,  elastic  and  permanent,  in 
which  properties  they  are  excelled  by  none  sold  in  the 
United  States  or  Europe. 
These  little  articles  will  be  found  of  great  value  and  convenience  in  the  hands  of  the  physi- 
cian who  studies  to  remove  the  objectionable  properties  of  the  medicines  which  he  deems  it 
necessary  to  employ. 
Many  drugs,  among  which  we  may  note  roots,  gums,  emetics,  capsicum,  etc.,  which — either  from 
the  more  immediate  effect  to  be  produced,  or  from  some  special  action  to  be  desired— the 
physician  proposes  to  administer  in  the  crude  or  powdered  state,  in  preference  to  any  form  of 
preparation,  are  practically  debarred  from  use  in  certain  cases  on  account  of  their  physical 
properties  (appearance,  odor,  taste),  and  the  difficulty  experienced  in  swallowing  them.  It  is 
frequently  advisable  to  conceal  from  the  patient  the  nature  or  identity  of  the  drug,  because  of 
some  idiosyncrasy,  or  of  his  imagination  with  regard  to  its  peculiar  effects  on  his  system. 
To  be  able  to  easily  disguise  these  features  of  a  remedy  at  the  bedside  of  a  patient,  at  a 
time  and  place  when  he  cannot  employ  the  assistance  of  a  pharmacist,  is  a  great  desideratum 
to  the  practitioner. 
Our  Capsules  will  fully  supply  this  want;  a  few  trials  will  demonstrate  all  their  advantages 
among  which  we  may  enumerate  the  following : 
Convenience.— A  box  (100  capsules)  can  be  carried  in  the  pocket  without  inconvenience, 
ready  for  use  as  desired.  They  may  be  filled  with  the  medicine  in  a  moment,  thoroughly  dis- 
guising its  appearance,  odor  and  taste,  and  are  easily  swallowed,  thus  gaining,  if  we  may  use  the 
phrase,  a  foothold  in  the  stomach  for  the  drug,  which  would  have  been  quickly  rejected  by  the 
patient  in  its  undisguised  itate. 
Solubility. — We  have  endeavored  to  so  prepare  our  gelatine  that  it  will  quickly  dissolve 
under  the  combined  action  of  the  warmth  and  moisture  of  the  stomach,  requiring  but  little 
digestive  action,  and  as  a  result,  our  capsules  can  be  employed  in  dyspepsia  and  •ther  forms  of  irritable 
or  torpid  stomach,  when  this  property  is  essential. 
Therapeutical  Effect,— The  gelatine  having  been  dissolved,  the  remedy  is  brought  into 
contact  with  the  surface  of  the  stomach  under  the  most  favorable  circumstances,  and,  if  the  case  will 
permit,  will  soon  be  assimilated,  and  the  desired  results  achieved. 
Emetics  are  exhibited  in  capsules  to  great  advantage,  and  quick  returns  may  be  con- 
fidently expected.  In  this  respect  capsules  are  in  contrast  to  pills,  which,  from  their  form  and 
constituents  gradually  dissolve  in  the  stomach,  producing  the  effects  desired  from  narcotics, 
tonics,  eic,  while  they  are  not  dissolved  rapidly  enough  for  the  use  to  which  powerful  emetics 
are  devoted. 
Administration. — Capsules  can,  of  course,  be  applied  to  the  administration  of  any  class 
of  medicines,  either  simple  or  in  combination  ;  yet  they  are  especially  designed  for  facilitating 
the  act  of  swallowing  such  articles  as  powdered  roots  and  gums  (which,  from  their  insoluble  or 
glutinous  nature,  are  liable  to  linger  in  the  mouth  too  long),  or  for  disguising  the  taste  of 
quinine,  morphine,  capsicum,  oils,  fluids  and  solid  extracts,  etc. 
Our  capsules  are  put  up  In  neat  sliding  paper  boxes,  containing  100  each,  for  which  we 
charge  fifty  cents  each,  We  will  mail  a  box  lo  any  address  on  receipt  of  the  price  and  three  cents 
postage. 
PARKE,  DAVI8  <fc  OO. 
Send  stamps  for  a  sample.  IDBTJIOIT,  1VEXCZE3Z. 
