228  Fluid  Extracts  by  Rep er eolation.      {Am-£yT,  J7^rm' 
The  following  table  gives  the  detail  of  these  observations  in  com- 
pact form,  but,  as  it  was  found  by  examination  of  the  residue  that  the 
strong  alcohol  did  not  fully  exhaust  the  Cimicifuga,  the  percolations 
were  only  carried  as  far  as  the  third,  at  which  point  it  was  determined 
to  try  a  new  menstruum,  in  another  process. 
Cimicifuga,  with  Stronger  Alcohol. 
Portions 
of 
Percolate. 
First  Percolation. 
Second  Percolation. 
Third  Percolation. 
Weight  of  Por- 
tion of  Per-  O 
colate  3 
Weight  of  Dry  3 
Extract.         <"  j 
Per  cent,  of  Dry 
Extract. 
6 
in 
0 
V 
5 
Weight  of  Por- 
tion of  Per-  O 
colate.  p 
Weight  of  Dry  3 
Extract.  ? 
Per  cent,  of  Dry 
Extract. 
6 
vi 
0 
8 
1 
5 
Weight  of  Por- 
tion of  Per-  O 
colate.  p 
Weight  of  Dry  g 
Extract.  V 
Per  cent,  of  Dry 
Extract. 
6 
0' 
D 
5J 
S 
3d.  
5th  
7th  
62*20 
65-35 
64-5i 
63-03 
6l'22 
60  24 
6lO0 
60  02 
65  37 
6i-86 
112-52 
108-01 
7-78 
625 
4-84 
3-36 
2-30 
1-69 
1  30 
1-29 
i'ii 
i'ii 
•91 
1-25 
12-51 
9'56 
7-5o 
5"33 
376 
280 
2-13 
2-15 
1 70 
1-79 
•81 
ri6 
•0444 
•0330 
•0264 
•0232 
•0184 
0140 
•on6 
•0108 
•0096 
•0028 
'0036 
•0016 
63-  41 
64-  23 
6312 
62-54 
61  65 
62  36 
63*11 
63'4i 
62-12 
62-32 
62-24 
63  33 
8o-oi 
98*00 
12-15 
808 
6  82 
4'22 
3*54 
2  90 
2  63 
2-21 
I-76 
i-53 
i'39 
1  16 
1-77 
1-90 
19-16 
12-58 
10.80 
6-74 
5*74 
4-65 
4-17 
3 '49 
2-83 
2-46 
2*23 
1  -8  3 
2*21 
I  94 
•0636 
•0440 
•0328 
■0240 
•0204 
•0164 
•0128 
•0104 
•0068 
•0044 
•0060 
•0044 
•0060 
•0052 
6l'22 
66-35 
64-30 
55-00 
62-00 
62-  22 
63-  34 
62-24 
62-  56 
63-  06 
64  02 
63-44 
62-32 
6680 
10-98 
8'53 
6'97 
4-79 
4'32 
3  38 
2*76 
2-51 
2-18 
1  98 
r8o 
i-68 
1*20 
•90 
17-93 
12-86 
1084 
8-71 
697 
5'43 
4'36 
4'o3 
3-48 
3-12 
2-81 
2*65 
1-92 
i'35 
•0556 
•0476 
•0372 
•0352 
•0272 
'0224 
•018+ 
•0148 
•0124 
•0096 
•0100 
"OIOO 
•0082 
•0018 
845-33 
33'i9 
18-87 
93I-85 
1  
52-06 
3i  27 
878-87 
53'98 
31-27 
Reserved  Extract- 
Extract  carried  for- 
H-32 
33*19 
20-79 
37-74 
22-71 
33-I9 
Extract  from  each 
The  first  percolation  of  the  table  being  simply  a  percolation  with 
fresh  menstruum  to  practical  exhaustion,  serves  to  compare  and  check 
the  other  percolations  in  their  results.  The  8  troyounces  of  Cimici- 
fuga =248*8  grams,  required  845*33  grams-  °f  percolate  for  practical 
exhaustion,  though  this  was  short  of  actual  exhaustion.  The  total  per- 
colate is  therefore  nearly  three  and  a  half  times  the  weight  of  the 
powder,  and  is  as  little  as  will  give  a  practical  exhaustion  of  this  drug 
with  this  menstruum.  This  is  more  than  double  the  proportion  of  the 
officinal  U.  S.  P.  formula,  and  accounts  for  a  part  of  the  defects  of  the 
officinal  preparation.    The  extract  obtained  for  this  first  percolation 
