Amj£e^8P7h8arl^•}         The  Cinchona  Alkaloids.  299 
readily  in  the  same  solvent  at  300  to  35°C.  Its  solution  is  translucent 
and  opalescent,  neutral  to  test  paper,  but  will  precipitate  oxide  of  iron 
in  flakes  after  standing  for  some  time.  On  gradually  adding  10  to  12 
drops  of  pure  muriatic  acid,  spec.  grav.  I'I2,  the  solution  becomes 
clear  ;  in  case  a  slight  turbidness  remains,  it  can  be  removed  by  filtra- 
tion. After  mentioning  that  Schlickum  was  unsuccessful  in  all  his 
experiments  with  dry  albuminate  of  iron,  there  being  always  an  insolu- 
ble residue  amounting  to  20  per  cent,  on  redissolving  the  coagulum  of 
chloride  of  iron  and  albumen  obtained  by  evaporating  to  dryness  ;  Dr. 
Hoffmann  suggests  to  mix  the  chloride  of  iron  and  albumen  in  a  certain 
proportion,  each  previously  reduced  to  a  fine  powder  ;  thus  the  insolu- 
ble residue'will  be  avoided.  He  operates  as  follows  :  15  parts  of  crys- 
tallized chloride  of  iron  (Fe2Cl6+i 2H20,  containing  20  per  cent,  ot 
metallic  iron),  or  20  parts  of  liquor  ferri  sesquichlorati  are  dried  with 
10  parts  of  dextrin  at  400  to  50°C,  and  pulverized  ;  then  80  parts  of 
pulverized  albumen  are  mixed  with  it.  The  latter  is  obtained  by  mix- 
ing fresh  albumen  with  half  its  weight  of  water,  setting  aside  for  several 
hours,  then  removing  the  membrane  by  straining,  and  finally  evaporat- 
ing on  flat  plates  at  a  temperature  of  300  to  40°C,  which  is  easily 
accomplished,  albumen  being  not  in  the  least  hygroscopic  ;  when  dry- 
it  is  easily  removed  from  the  plates.  The  author  considers  this  dry 
albuminate  of  iron  by  far  preferable  for  making  Triese's  solution,  claim- 
ing that  in  this  manner  the  solution  will  always  have  a  uniform  taste* 
composition  and  strength. — Phar.  Zeitung,  March  23  and  30. 
THE  CINCHONA  ALKALOIDS. 
By  O.  Hesse. 
Translated  and  condensed  from  "  Berichte  der  Deutschen  Chemischen  Gesellschaft,"  1877,  p.  2152 — 2162,. 
by  L.  v.  Cotzhausen,  Ph.G. 
§)uinia,  C20H24N2O2.  Precipitated  by  ammonia  or  soda,  it  is  amor- 
phous and  anhydrous,  but  soon  combines  with  3H20,  forming  small 
crystals.  Both  the  anhydrid  and  trihydrate  are  readily  soluble  in  ether, 
which  on  slow  evaporation  yields  some  fine  white  needles  ;  the  balance, 
at  first  amorphous,  becomes  crystalline  after  some  time.  The  etherial 
solution  sometimes  gelatinizes  suddenly  from  the  separation  of  quinia, 
which  is  then  less  freely  soluble  in  ether,  requiring  at  I5°C.  for  I  part  of 
quinia  (anhydrous)  16  to  25*5  parts  of  ether  to  effect  solution.  The 
anhydrid  fuses  at  ijj°C,  the  trihydrate  at  57°C.  ;  the  former  dissolves 
