442 
Fluid  Extract  of  Cimicifuga. 
{Am.  Jour.  Pharm. 
Sept.,  1878. 
The  former  fell  behind  corresponding  experiment  at  ordinary  tempera- 
ture (see  Table  2,  January  "  Journal").  The  latter  surpassed  any- 
thing which  has  been  offered,  and  the  indications  are  that  this  increase 
of  value  resulted  from  the  mode  of  percolation,  in  conjunction  with 
the  temperature. 
I  have  taken  it  for  granted  that  the  increase  in  the  extractive  matter 
by  maceration  and  heat  are  an  advantage  to  the  finished  extract.  I 
have  made  my  calculations  on  the  supposition  that  the  value  of  the 
extract  varies  with  the  proportion  of  extractive  matter,  a  point  I  have 
experimented  much  on,  though  not  yet  presented. 
From  those  interested  in  my  article  in  the  January  number  I  have 
have  received  many  suggestions,  but  I  cannot  touch  now  upon  all  the 
points,  wishing  to  avoid  wandering,  and  to  confine  my  remarks  to  a 
few  points  that  may  be  considered  with  regard  to  the  experiments  given 
in  each  article.  It  will  not  do  to  make  generalizations  unaccompanied 
with  reasons  for  same,  and  to  give  tables  and  remarks  for  even  a  few 
of  the  important  points  that  suggest  themselves  would  require  more 
space  than  could  be  placed  at  my  disposal. 
If  I  have  made  any  unjust  comparisons  I  will  consider  it  a  kindness 
to  be  informed  of  the  fact.  There  are  errors  creeping  into  all  lines  of 
experiments,  but  they  can  generally  be  corrected. 
To  Prof.  Hough,  of  this  city,  I  express  my  gratitude  for  the  tedious 
check  weighing  he  made  of  a  very  important  portion  of  the  experi- 
ments offered  in  the  January  number.  In  answer  to  the  question 
which  ended  the  article  in  that  number,  I  think  it  may  be  safely 
said,  We  can,  perhaps,  though  we  must  increase  the  material  worked, 
and  decrease  the  percolate  obtained,  if  we  apply  the  principle  econom- 
ically. 
Note  by  the  Editor. — It  is  due  to  Mr.  Lloyd  to  state  that  the 
paper  intended  as  a  continuation  of  his  essay  closing  on  page  15  of  the 
present  volume  was,  after  a  delay  occasioned  by  fire,  received  by  us 
while  Dr.  Squibb's  paper  on  page  209  was  in  the  printer's  hand.  At 
our  request  Mr.  Lloyd  withdrew  that  paper  and  consented  to  go  again 
over  the  same  ground. 
