340 
Dialyzed  Iron. 
I  Am.  Jeur.  Phartn. 
1       July,  1877. 
Hypophosphite  of  berberina  is  a  beautiful  yellow  salt,  much  more 
soluble  than  the  muriate. 
By  substituting  other  acids  for  the  hypoposphorous  almost  any  salt  of 
berberina  can  be  easily  formed.  When  free  from  foreign  substances, 
I  have  failed  to  find  any  salt  of  this  alkaloid  as  soluble  in  cold  water  as 
the  berberina  itself,  but  the  hypophosphite  will  dissolve  readily  to  a 
considerable  extent,  and  is  the  most  desirable  form  I  am  acquainted 
with. 
DIALYZED  IRON. 
By  Andrew  and  H.  C.  Blair. 
This  preparation  has  attracted  the  attention  of  many  of  the  pharm- 
acists and  medical  profession  of  Europe  for  some  time  past,  and  the 
experience  resulting  from  its  use  is  so  satisfactory,  peculiar  and  won- 
derful, that  it  is  probably  destined  soon  to  become  one  of  our  most 
valued  therapeutic  agents  in  a  large  class  of  diseases  where  the  ordinary 
iron  preparations  are  objectionable.  "  With  this  preparation,"  says  an 
author,  "  we  are  able  now  to  avoid  all  inconveniences  which  arise  from 
the  employment  of  ordinary  ferruginous  preparations." 
Our  attention  was  called  to  it  some  months  ago  through  corres- 
pondence with  a  customer  residing  abroad,  who  spoke  so  highly  of  it, 
and  mentioned  such  peculiar  and  wonderful  properties  it  possessed,  that 
led  us  to  inquire  more  particularly  into  it.  Further  correspondence 
stated  that  this  party  had  taken  it  as  a  remedial  agent  for  a  protracted 
period  without  the  least  inconvenience  or  unpleasant  effect,  and  while 
under  treatment  in  this  country  for  the  same  ailment,  the  ordinary  iron 
preparations  were  prescribed,  but  could  not  be  taken  for  any  consider- 
able time  without  experiencing  the  common  trouble  so  frequently  com- 
plained of — headache,  constipation,  etc.  Being  interested  in  the  mat- 
ter, we  obtained  from  a  prominent  French  chemist  a  formula  by  which 
he  was  in  the  habit  of  making  it,  which  is  in  substance  as  follows  : 
Take  10  parts  liq.  ferri  per.  chlor.  (Br.  Ph.),  precipitate  by  aqua 
ammoniac  and  wash  the  precipitate  thoroughly.  Mix  this  with  12  parts 
of  liq.  ferri  perchlor.  (Br.  Ph.),  and  place  in  a  dialyzer.  The  dialyzer 
is  placed  in  a  suitable  vessel  with  distilled  water,  the  water  under  it 
renewed  every  24  hours.  The  operation  is  continued  until  no  trace  of 
chlorine  exists,  at  which  time  the  preparation  is  found  to  be  neutral. 
It  usually  takes  from  12  to  15  days  to  complete  the  process. 
