Amji°y,r'i8P77arm'}    Extr actum  Glycyrrhiz<e  Depuratum.  347 
tion.  Its  use  appears  also  to  be  indicated  for  those  drugs  the  active 
principles  of  which  are  soluble  in  water  and  dilute  alcohol.  In  fluid 
extracts  of  mucilaginous  drugs  like  pleurisy  root  it  cannot  be  used  to 
any  great  extent,  and  it  is  best  discarded  altogether  in  all  cases  where 
the  active  principle  is  of  a  resinous  nature. 
EXTR  ACTUM   GLYCYRRHIZ^   DEPURATUM  AND 
'     AM  MO  NX  AC  AL  GLYCYRRHIZIN. 
By  Gustav  A.  Appenzeller,  Ph.G. 
From  an  Inaugural  Essay. 
The  author  recommends  to  dispense  in  liquid  preparations,  and  more 
particularly  in  the  officinal  Mist.  Glycyrrh.  comp.,  the  purified  extract 
of  liquorice  of  the  German  Pharmacopoeia  in  place  of  powdered  liquorice. 
It  is  prepared  by  putting  into  a  suitable  vessel  alternate  layers  of  straw 
and  commercial  liquorice,  covering  with  cold  filtered  water,  drawing 
off  the  liquid  from  time  to  time  and  evaporating  to  the  consistence  of 
a  thick  syrup.  It  yields  a  clear  solution  with  water,  and  an  excellent 
syrup  of  liquorice  may  be  prepared  from  it  by  mixing  one  ounce  with  a 
pint  of  simple  syrup. 
The  following  brands  of  liquorice  yielded  the  amounts  of  extract 
[of  what  consistence?]  stated  below:  Duca  di  Corigliana  77*24,  M. 
&  R.  72-66,  P.  &  S.  61*22,  A.  &  S.  60*91,  and  Noely  58*92  per  cent. 
The  residues,  insoluble  in  cold  water,  had  a  similar  appearance,  and 
contained  starch. 
Ammoniacal  glycyrrhixin  was  prepared  according  to  Roussin,  by 
exhausting  the  bruised  root  with  little  water,  boiling  the  liquid,  remov- 
ing the  coagulated  albumen,  precipitating  with  hydrochloric  acid, 
washing  the  precipitate,  dissolving  in  ammonia  and  drying  upon  glass, 
when  yellowish  scales  having  the  taste  of  the  root  were  obtained. 
By  exhausting  the  root  with  diluted  ammonia  water,  evaporating  and 
drying  on  glass,  a  considerably  larger  quantity  of  somewhat  darker 
colored  scales  were  obtained.  A  similar  but  still  darker  colored  pre- 
paration results  if  liquorice  is  treated  in  the  same  manner.  The  scales 
made  from  the  root  are  more  pleasant  in  taste,  particularly  if  Russian 
liquorice  root,  deprived  of  the  brown  cortical  layer,  is  used. 
