AmNJo0vU,ri8P77arm}  Constituents  of  Podophyllum  Peltatum.  549 
cent,  of  its  weight.  This  portion  dissolved  in  alcohol  with  a  light- 
brown  color  ;  the  solution  had  a  bitterish  taste,  and  was  precipitated 
light-greyish  by  water,  bright-yellow  by  alum  solution  and  orange-yel- 
low by  alcoholic  solution  of  lead  acetate.  All  the  precipitates  dissolve 
to  some  extent  in  hot  water,  most  of  the  dissolved  portion  being  repre- 
cipitated  on  cooling.  The  alum  precipitate  left  1*25  per  cent,  of  ash, 
consisting  of  alumina  ;  the  resin  obtained  by  evaporating  the  ether  left 
no  fixed  residue. 
Resin  Insoluble  in  Ether. — It  was  found  to  have  a  bitter  taste  and  to 
be  soluble  in  alcohol  and  alkalies,  and  slightly  so  in  water.  The  alco- 
holic solution  became  turbid  on  the  addition  of  water,  and  very  gradu- 
ally yielded  a  greyish  precipitate  ;  acidulated  water  produced  a  similar 
precipitate,  solutions  of  alum  and  of  acetate  of  lead  somewhat  darker, 
but  not  yellow  precipitates.  The  bright-yellow  color  of  the  resin  pre- 
pared with  alum  solution  is  therefore  due  only  to  the  resin  soluble  in 
ether. 
The  aqueous  solutions  of  both  resins  gave  no  reaction  with  Mayer's 
solution,  except  in  one  instance  ;  their  alkaline  solutions  were  of  a 
yellowish-brown  color,  when  sufficiently  diluted  with  water  were  not 
precipitated  by  acids,  and  after  having  been  boiled  with  dilute  hydro- 
chloric acid  gave  no  indication  of  sugar  with  Trommer's  test. 
Principles  Soluble  in  Water. — The  tincture  precipitated  with  acidu- 
lated water  yielded  a  reddish  filtrate,  of  a  very  bitter  taste,  and  con- 
taining sugar,  as  indicated  by  Trommer's  test.  On  concentrating  the 
solution,  an  amorphous  bitter  mass  separated,  which  dissolved  in  alco- 
hol, but  could  not  be  obtained  in  a  crystalline  state. 
The  filtrate  obtained  by  precipitating  with  alum  solution  was  like- 
wise bitter,  and  on  being  concentrated  changed  to  ruby-red  and  sepa- 
rated crystals  of  alum  ;  a  blackish,  semi-fluid,  bitter  substance  was 
likewise  separated,  which  was  insoluble  in  ether,  carbon  bisulphide  and 
petroleum  benzin,  but  dissolved  in  alcohol  and  warm  water.  It  was 
not  obtained  in  a  crystallized  state. 
On  mixing  the  tincture  of  the  rhizome  of  podophyllum  with  ether 
a  dark-colored  mass  separated,  which  had  a  very  bitter  taste,  but  con- 
tained sugar,  as  indicated  by  Trommer's  test. 
