22  Revision  of  the  U.  S.  Pharmacopeia.  {*mi£Zim™m' 
trate  to  be  made  up  to  550  cc.  by  washing  the  precipitate.  The  pre- 
cipitate cannot  occupy  the  space  of  255  cc.  of  the  liquid.  The  600  cc. 
of  infusion  should  be  directed  to  be  evaporated  to  400  cc,  and  then 
the  alcohol  and  oil  of  coriander  added  and  the  process  continued  as 
in  the  official  direction. 
The  tinctures  as  a  class  show  a  decided  improvement.  With  but 
one  exception,  and  that,  most  likely  unintentional,  the  formulas  are 
given  for  the  uniform  quantity  of  1  liter  of  product.  In  Tincture  of 
Aconite  the  suggestion  of  Tscheppe  to  reduce  the  alcoholic  strength 
of  the  menstruum  has  been  accepted  and  7  vols,  alcohol,  3  vols, 
water  now  are  directed  in  place  of  alcohol  of  the  previous  edition. 
In  Tincture  of  Aloes,  liquorice  root  is  now  directed  in  place  of 
the  extract  and  percolation  is  ordered  instead  of  maceration. 
Liquorice  root  is  likewise  added  to  the  Tincture  of  Aloes  and 
Myrrh,  an  unnecessary  addition.  I  would  prefer  maceration  to  per- 
colation in  both  of  these  tinctures. 
In  Tincture  of  Arnica  the  arnica  flowers  in  No.  20  powder  are  to 
be  packed  into  a  cylindrical  percolator,  without  previous  moistening. 
We  cannot  see  why  this  exception  should  be  made  to  the  generally 
adopted  rule  of  moistening  the  powder  before  packing. 
The  adoption  of  alcohol  in  place  of  diluted  alcohol  for  Tincture 
of  Calendula  is  a  change  that  cannot  be  approved.  Diluted  alcohol 
even  of  the  strength  of  the  Pharmacopoeia  of  1880  extracted  this 
drug  and  yielded  a  permanent  tincture  The  use  to  which  this  pre- 
paration is  generally  applied,  namely,  external  application  to  wounds, 
bruises,  etc.,  makes  strong  alcohol  undesirable  as  the  menstruum. 
The  Pharmacopoeia  of  1880  reduced  the  strength  of  Tincture  of 
Indian  Cannabis  and  it  now  suffers  another  reduction  of  nearly  5 
per  cent,  in  the  amount  of  the  drug  used,  equivalent  to  a  reduction 
of  nearly  25  per  cent,  in  strength. 
Tincture  of  Cinnamon  is  now  to  be  made  from  the  Ceylon  cinna- 
mon and  contains  5  per  cent,  by  volume  of  glycerin. 
In  Tincture  of  Cubebs  the  menstruum  becomes  alcohol  in  place 
of  diluted  alcohol  and  the  drug  strength  is  doubled.  Both  of  these 
are  good  changes. 
In  the  formula  given  for  Tinctures  of  Fresh  Herbs,  the  amount  of 
product  to  be  obtained  is  not  stated.  This  would  vary  with  the 
amount  of  moisture  present  in  the  various  herbs.  It  evidently  was 
the  intention  to  direct  that  the  so-called  50  per  cent,  tincture  should 
