Am'jaT"i?94arm'}  Revision  of  the  U.  S.  Pharmacopoeia.  23 
be  obtained,  that  is  50  gm.  of  the  fresh  drug  to  be  represented  by 
IOO  cc.  of  the  finished  tincture.  In  order  to  attain  this  object  but 
900  cc.  of  alcohol  should  be  directed  to  be  used  in  the  maceration 
and  then  the  residue  after  expression  and  the  filter  washed  with 
sufficient  alcohol  to  obtain  1,000  cc.  of  tincture. 
The  increase  in  alcoholic  strength  of  the  menstruum  used  for  Tinc- 
ture of  Galls  and  the  reduction  in  that  directed  for  Tincture  of  Gel- 
semium  are  both  good  changes. 
In  the  Compound  Tincture  of  Gentian,  it  is  to  be  noted  that  the 
amount  of  Cardamom  has  been  reduced  one-half.  We  doubt  if  too 
much  aromatic  material  could  be  introduced  in  this  preparation. 
Tincture  of  Lactucarium  is  introduced  solely  for  the  purpose  of 
making  therefrom  the  syrup.  As  a  substitute  for  the  unsatisfac- 
tory and  difficult  to  prepare  fluid  extract  of  1880,  it  is  a  welcome 
addition. 
Elsewhere,  the  writer  has  called  attention  to  the  impossibility  of 
preparing  Tincture  of  Musk,  containing  10  per  cent,  of  musk,  as 
directed  by  the  Pharmacopoeia  of  1880,  and  attempted  to  prove 
that  even  in  a  tincture  containing  2  per  cent,  of  pure  musk  it  was 
not  completely  extracted.  In  the  new  edition,  the  first  proposition 
appears  to  be  recognized,  and  now  the  tincture  is  directed  to  be 
made  50  gm.  in  1,000  cc,  about  5  per  cent.  To  have  made  it  2  per 
cent,  would  have  brought  it  in  harmony  with  the  German  Pharma- 
copoeia and  as  strong  as  a  tincture  of  pure  musk  can  be  made. 
If  the  official  directions  for  preparing  Tincture  of  Nux  Vomica 
are  followed,  using  only  extract  of  nux  vomica  corresponding 
to  the  official  requirements,  an  active  remedy  must  result.  In 
future,  tincture  of  nux  vomica  from  all  sources  should  be  uniform. 
The  formula  for  Tincture  of  Opium  is  likewise  excellent,  and 
with  the  morphine  strength  of  powdered  opium,  as  limited  by 
the  Pharmacopoeia,  there  remains  no  excuse  for  the  want  of  uni- 
formity in  this  preparation  as  supplied  by  different  pharmacists. 
Tinctures  of  Physostigma  and  Stramonium  Seed  have  been 
increased  nearly  50  per  cent,  in  strength,  there  now  being  150  gm. 
of  the  drug  in  1,000  cc,  instead  of  10  per  cent.  This  strength 
has  been  adopted  for  many  of  the  tinctures  of  poisonous  drugs. 
Tincture  of  Quillaia  is  a  new  addition,  being  a  concentrated 
decoction,  with  the  addition  of  35  per  cent,  by  volume  of  alcohol 
as  a  preservative. 
