492  Ohio  State  Pharmaceutical  Association.    {A October, K111' 
ively  4-15  c.c.,  4  c.c.  and  12  8  c.c.  of  normal  potassium  hydrate 
volumetric  solution. 
This  excessive  acidity  was  found  to  be  due  to  acetic  acid,  result- 
ing from  the  gradual  decomposition  of  the  paraldehyde  through 
long  standing  and  exposure  to  air.  Foreign  aldehydes  were  absent. 
Potassii  Bitartras. — The  official  requirements  were  met  by  the 
two  samples  investigated. 
Spiritus  Aitheris  Nitrosi. — All  four  of  the  products  assayed  were 
acid.  Three  contained  aldehyde.  The  preparations  averaged  a 
content  of  1  per  cent,  of  ethyl  nitrite. 
Zinci  Oxidum. — Two  of  the  three  lots  subjected  to  analysis  pos- 
sessed a  slightly  styptic  taste,  due  to  the  presence  of  07  per  cent, 
and  0-27  per  cent,  of  zinc  sulphate.  They  showed  o  32  per  cent., 
ri6  per  cent.,  and  0.257  per  cent,  of  lead  oxide.  One  contained 
carbonate.    All  were  free  from  arsenic,  cadmium,  and  silicate. 
LACTOPHENINE. 
According  to  a  note  in  Jour,  de  Pharm.  et  de  Chun.  [5]  29>  41 5> 
lactophenine  is  related  to  phenacetine  as  follows  : 
Phenacetine  is  an  acetyl  derivation  of  paraphenetidine. 
CH/OCH5  CH/OC2H5 
6  J\NH„  6  4\NH  (COCH3) 
Paraphenetidine.  Phenacetine. 
Lactophenine  is  phenacetine  in  which  the  acetic  residue  is  replaced 
by  that  of  lactic  acid  ;  it  is  therefore  a  lactic  residue  of  paraphenet- 
idine ;  it  is  a  white  inodorous  powder,  soluble  in  330  parts  of  water. 
Dr.  Jaksch  has  employed  it  in  abdominal  typhus.  This  remedy  is 
administered  in  doses  of  5  to  1 5  grains.  A  total  of  90  grains  may 
be  administered  in  the  course  of  a  day.  In  the  smaller  doses  it  acts 
as  an  analgesic,  in  larger  doses  as  an  hypnotic. 
1,739,081  troy  ounces  of  gold  were  produced  in  the  United  States 
in  1893,  having  a  coining  value  of  35,950,000  dollars.  The  silver 
during  the  same  period  amounted  to  60,500,000  troy  ounces,  with 
a  coining  value  of  78,220,450  dollars. 
