432 
Progress  in  Pharmacy. 
(km.  Jour.  Pharm. 
\  September,  1914. 
malarial  mosquitoes  or  to  properly  screen  against  them. — /.  Am. 
M.  Assoc.,  1914,  vol.  62,  p.  2042. 
Quinine  in  the  Treatment  of  Syphilis.  (Breitmenn,  M.  J.) — The 
observation  that  the  administration  of  quinine  for  the  treatment  of 
malaria  in  patients  infected  with  syphilis  was  invariably  accompanied 
by  marked  improvement  of  secondary  and  tertiary  manifestations  of 
the  latter  disease  led  to  further  experimentation  and  the  use  of  a 
mixture  of  quinine  muriate  3,  with  antipyrin  2,  dissolved  in  from  6 
to  8  c.c.  of  warm  water.  This  mixture,  designated  chinopyrin,  is  in- 
jected subcutaneously  and  has  given  promising  results. — Therap. 
Monatsh.,  1914,  vol.  28,  pp.  504,  505. 
Results  of  Radium  in  Cancer.  (Janeway,  H.  H.) — A  survey  of 
reported  results,  with  the  suggestion  that  a  more  successful  method 
of  applying  radium  may  yet  be  discovered  and  that  the  whole  question 
may  reduce  itself  to  the  even  distribution  of  the  proper  dosage 
throughout  all  invol-ved  tissues.  At  the  present  time  radium  may 
only  supplement  but  not  replace  the  knife. — /.  Am.  M.  Assoc.,  1914, 
vol.  62,  pp.  1 707-1 709. 
Dangers  from  Radium  Treatment  of  Cancer.  (Rovsing,  T.)  — 
Tragic  experiences  in  a  number  of  cases  lead  to  the  conclusion  that 
radium  promotes  instead  of  checks  cancer. — Hospitalstid.,  1914, 
vol.  62,  >N.  27.)    /.  Am.  M.  Assoc.,  1914,  vol.  63,  p.  520. 
Production  of  Metallic  Uranium.  {Anon.) — The  steady  increase 
in  the  production  of  radium  at  S.  Joachimsthal,  Austria,  has  resulted 
in  an  overproduction  of  uranium  salts,  which  up  to  the  present  time 
are  used  only  as  coloring  for  glass  and  porcelain  and.  have,  therefore, 
but  a  limited  application.  Attempts  have  recently  been  made  to  pro- 
duce metallic  uranium  by  an  electrolytic  method,  and  these  efforts 
promise  to  be  successful.  Further  experiments  are  being  undertaken 
with  a  view  to  utilizing  the  resulting  material  in  the  production  of 
amalgams,  more  particularly  the  utilization  of  metallic  uranium  in 
the  improvement  of  steel. — Pharm.  Post,  1914,  vol.  47,  p.  557. 
Pharmacological  Instability  of  Scopolamine  in  Ampoules. 
(Langer,  H.) — To  determine  the  pharmacological  activity  of  scopo- 
lamine solutions,  recourse  was  had  to  its  antidotal  action  on  muscarine 
in  the  isolated  frog's  heart.  This  test  is  quantitative,  and  much  more 
reliable  than  the  production  of  mydriasis  in  the  cat's  eye.  From  tests 
with  the  muscarine  method,  it  is  found  that  scopolamine  salts  kept 
in  ampoules  soon  deteriorate,  losing  their  specific  action.  Solutions 
of  scopolamine  for  therapeutic  use,  therefore,  should  be  freshly  pre- 
