7o 
Syrupus  Aurantii. 
f  Am.  Jour.  Pbarm. 
\    February,  1900. 
prepared  from  the  peel  subjected  to  extraction  with  alcohol  in  the 
cold. 
This  is  the  principle  upon  which  the  formulas  of  the  1870  and 
1880  Pharmacopoeias  are  based. 
It  appears,  however,  that  the  percentage  of  alcohol  retained  in 
the  present  syrup  is  excessive,  and  a  more  satisfactory  preparation 
is  obtained  if  the  alcohol  is  partly  allowed  to  evaporate. 
A  syrup  of  less  spirituous  flavor  is  thereby  produced. 
The  following  formula  is  based  upon  this  principle,  with  retention 
of  the  precipitated  calcium  phosphate  as  medium  for  filtration  : 
Macerate  the  sweet  orange  peel,  which  should  be  as  free  as  pos- 
sible from  the  white  inner  layer,  and  grated,  in  1 00  c.c.  of  alcohol 
during  twenty-four  hours. 
Pour  the  mixture  into  a  narrow  percolator,  allow  the  alcoholic 
extract  to  drain,  and  continue  the  percolation  with  small  portions 
of  alcohol  until  I OO  c.c.  of  percolate  have  been  obtained. 
Mix  the  precipitated  calcium  phosphate  in  a  mortar  with  150 
grammes  of  sugar  and  add  the  tincture  with  constant  trituration. 
Set  the  mixture  aside  in  a  moderately  warm  place  until  the 
greater  portion  of  the  alcohol  has  evaporated. 
To  the  residue  add  300  c.c.  of  water,  transfer  the  whole  to  a 
filter  and  return  the  first  portions  of  the  filtrate,  if  necessary,  until  it 
runs  clear. 
In  the  filtrate  dissolve  the  remainder  of  the  sugar  by  agitation 
without  heat,  and  add  a  sufficient  quantity  of  water  to  make  the 
product  measure  1,000  c.c.    Strain  if  necessary. 
While  conducting  the  above  experiments,  magnesium  carbonate 
was  substituted  for  precipitated  calcium  phosphate  in  a  number  of 
instances. 
The  syrup,  prepared  by  filtration  through  magnesia,  possesses  a 
more  attractive  appearance,  has  a  brilliant  color  and  pleasant  odor 
and  taste. 
The  writer  regards  it  as  superior  to  syrup  prepared  by  filtration 
through  calcium  phosphate. 
SYRUPUS  AURANTII. 
Sweet  orange  peel,  taken  from  the  fresh  fruit 
Precipitated  calcium  phosphate  
Sugar  
Alcohol  1 
j"  of  each  a  sufficient  quantity  to  make  1,000  c.c. 
50  grammes. 
50 
75o 
