n8 
Synthetic  Chemicals. 
/Am.  Jour.  Pharm. 
t      March,  1900. 
Febrinol  is  a  preparation  of  very  similar  composition,  although  it 
is  held  out  to  the  profession  as  "  methyl-para-acet-phenetidin." 
There  is  a  compound  corresponding  to  this  designation,  listed  by 
Coblentz  as  methyl  phenacetin,  and  stated  to  have  hypnotic  prop- 
erties. It  is  not  known  to  us,  but  is  stated  to  have  a  melting  point 
of  400  C,  while  the  crystalline  substance  extracted  by  ether  from 
febrinol  melts  at  112°  C,  and  is,  in  fact,  acetanilid.  Following  is 
the  complete  analysis  of  febrinol : 
Per  Cent. 
Acetanilid  4979 
Sodium  bicarbonate   .  .  .  34'28 
"      carbonate  ,  -  4/03 
Sugar  11-59 
99*69 
Puronal  is  held  out  as  a  valuable  remedy  for  external  use  on 
ulcers,  etc.,  and  internally  in  fermentative  conditions  of  the  alimen- 
tary canal.  It  is  described  on  the  label  as  "  The  tetra  methylate  ot 
phenol,  iodine  and  bismuth."    Analysis  gave  the  following  results: 
PerCent. 
Acetanilid  97*22 
Bismuth  oxyiodide  2*35 
99'57 
Phecine  is  described  in  literature  accompanying  it  as  "  sulpho- 
metadihydroxy  benzene,"  with  the  formula  C6H4(OH)2S04.  Its 
composition  is  as  follows  : 
Per  Cent. 
Resorcinol —  C6H4(OH)2   81*30 
Zinc  sulphocarbolate   18*45 
•  —  99  75 
Iatrol  is  a  preparation  held  out  as  a  substitute  for  iodoform.  It 
is  described  by  Coblentz  as  "  oxy-iodo-  methyl-anilid,  obtained  by 
the  action  of  iodine  on  an  aniline  derivative."  Thorns  gives  it  the 
same  designation,  but  says  that  little  is  known  of  the  details  of  its 
preparation.  Both  authors  must  have  accepted  the  statements  of 
the  manufacturers  as  to  its  composition,  for  no  such  constitution  can 
be  made  out  from  the  sample  we  examined.  It  has  a  melting  point 
of  1120  C,  and  gives  all  the  reactions  of  acetanilid.  The  percentage 
of  nitrogen  is  10*23,  corresponding  to  98-65  per  cent,  acetanilid.  On 
shaking  with  carbon  disulphide,  a  slight  trace  of  iodine  was  obtained, 
which  may  come  from  a  minute  addition  of  aristol,  as  it  seems  to 
have  the  faint  odor  of  that  substance. 
