470 
Syrup  Ferrous  Iodide. 
f  A.m.  Jour.  Pharm. 
I     October,  1900. 
By  way  of  summary,  then,  we  note  that  glycerin  is  a  preservative 
by  simply  preventing  oxidation. 
That  it  assimilates  iodine,  after  liberation,  in  a  non-irritating 
form,  in  which  form  it  may  be  easily  taken  up  by  the  system,  as 
iodine,  and  does  not  act  as  an  iron  preparation. 
That  glycerin  is  not  objectionable  in  the  preparation,  as  it  is  an 
easily  assimilated  food  for  the  organism. 
That  glucose  is  a  better  preservative;  in  fact,  a  good,  almost  ideal 
preservative,  acting,  as  it  does,  both  by  preventing  oxidation  and 
reducing  the  iodine  after  liberation. 
That  as  a  product  of  oxidation  we  get  ferrous  oxide  and  free 
iodine,  and  by  reduction  we  have  formed  hydriodic  acid,  and  ferric 
sesquioxide  by  final  oxidation. 
That,  medicinally,  glucose  is  a  directly  fermentable  sugar,  easily 
digested,  in  fact,  a  partially  predigested  food. 
That  glucose  is  medicinally  valuable,  inducing  copious  polyuria  ; 
does  not  pass  into  the  urine,  but  is  oxidized  and  -consumed  in  the 
organism,  thus  acting  as  a  typical  food. 
Then  : 
Mol.  Mol. 
Wgt.  Wgt. 
Fel2  :    Is    :  :  X  (gramme  Fel2  remaining  in  ioo  c.c.)  :  107732  grammes  I  (as  Fel2). 
308  94  :  253  06  :  :  X  (gramme  Fel2  remaining  in  100  c.c.)  :  107732  grammes  I  (as  Fel2). 
253*06  X  =  3328*232408  grammes. 
X  =     131124  grammes  Fel2  remaining  in  100  c.c.  of  preparation. 
Now,  as  we  have  seen  above, 
14  grammes  =  10  per  cent,  by  weight  Fel2  in  glucose  preparation  (specific  gravity,  1*40), 
therefore, 
i3,H24  grammes  =  9  358  per  cent,  by  weight  Fel2  remaining  after  reduction  ; 
remembering  that  to  accomplish  this  degree  of  reduction  would  require  a  pro- 
longed period  of  continued  decomposition  and  reduction. 
The  formula  for  preparation  should  read  : 
Iron  (in  bright  wire)  27  grammes  (an  excess). 
Iodine  (resublimed)  8672  " 
Glucose  solution  (specific  gravity,  1*40). 
Distilled  water   ....  120  c.c. 
To  make  1,000  grammes. 
Standardize  the  finished  preparation  to  10  per  cent,  by  weight  strength  by 
the  usual  method  of  adding  an  excess  of      V.  S.  AgN03,  diluted  HN03  and 
10 
[Fe2(NH4)2(S04)4  -f  24H20]  V.  S.  and  titrating  back  the  excess  of  —  V.  S. 
10 
AgN03  with      V.  S.  KCNS  to  permanent  tinting. 
