Am.  Tour.  Pharm. 
May,  19 18. 
} 
The  New  Remedies  of  1917. 
367 
ments,  and  its  toxicity  is  much  lower  than  that  of  mercuric  chloride. 
ONa 
[     I  no2 
Acet ozone,  which  is  a  mixture  of  benzoyl-acetyl  peroxide  with  an 
inert  powder,  is  not  new,  but  its  use  has  been  confined  to  that  of  an 
intestinal  antiseptic.  It  has  now  been  found  to  be  of  service  in 
military  surgery  as  a  dressing  for  wounds.  It  is  non-toxic  and  in- 
nocuous to  the  tissues ;  its  solutions  are  colorless  and  do  not  stain, 
and  its  action  is  rapid. 
Among  other  antiseptics  that  have  received  favorable  comment 
are  Bacterol,  a  formaldehyde-iodine  compound,  and  Yadil,  described 
as  a  trimethenal  allylic  compound.  The  former  is  issued  in  several 
forms,  according  to  the  use  for  which  it  is  intended,  while  the  latter 
claims  to  be  absolutely  non-toxic — so  much  so  that  it  can  be  given 
internally  in  teaspoonful  doses. 
An  important  pronouncement  regarding  antiseptics  was  made 
early  in  the  year  by  Kenneth  Taylor,  who  declares  that  just  as  each 
disease  requires  its  own  specific  drug,  so  each  organism  can  be  con- 
trolled only  by  its  own  specific  antiseptic.  This  specificity  of  anti- 
septics opens  up  an  immense  field  for  research,  and  if  confirmed 
will  do  away  once  for  all  with  the  idea  of  a  general  antiseptic  for  all 
purposes.  It  will  also  account  for  the  varying  reports  received  from 
different  quarters  regarding  certain  antiseptic  substances. 
Bismuth-iodoform-paraffin  paste,  or  "  Bipp,"  has  now  many  ad- 
vocates. Its  use  in  wound  treatment  has  spread  considerably  during 
the  year.  The  paste  consists  of  bismuth  subnitrate,  1 ;  iodoform,  2 ; 
liquid  paraffin,  q.s.,  and  it  is  applied  freely  to  the  wound,  which  is 
entirely  filled  with  the  paste  and  dressed  with  sterile  gauze.  In  pre- 
paring "  Bipp "  great  care  must  be  taken  to  ensure  freedom  from 
grit. 
Paraffin  Treatment  of  Burns. — The  use  of  a  French  pro- 
prietary called  Ambrine  was  announced  comparatively  early  in  the  war. 
Ambrine  is  a  preparation  of  hard  paraffin,  containing,  some  say,  resin 
;ind  oil  of  amber.  When  melted  and  applied  to  burns  or  wounds,  it 
forms  an  air-tight  coating  under  which  the  lesion  rapidly  and  com- 
pletely heals.  Its  success  was  undoubted,  and  it  was  not  long  before 
investigations  were  afoot  with  a  view  to  ascertain  the  rationale  of  its 
HgOH 
