Am'DecUr'i9Pi8arnl'  ^        Determination  of  Morphine.  857 
treated  according  to  the  method  described  above,  the  volumes  of 
liquid  employed  being  those  there  mentioned.  The  morphine  found 
by  titration  was  therefore  10/22  of  the  whole,  or  that  present  in 
30/11  Gm.  of  opium. 
Titration  Results. 
Total  acid  used  =  26.00  Cc. 
Acid  equivalent  to  the  alkali  =  15-65  Cc. 
Acid  equivalent  to  the  morphine  =  10.35  Cc. 
Since  1  Cc.  acid  =  0.0300  Gm.  G7H19NO3  •  H20  crystallized 
morphine  found  =  0.3105  Gm. 
=  11.3  Per  Cent. 
Experiment  32. — This  was  a  check  determination,  duplicating 
Experiment  31. 
Titration  Results. 
Total  acid  used  =  25.00  Cc. 
Acid  equivalent  to  the  alkali  =  14.71  Cc. 
Acid  equivalent  to  the  morphine  =  10.29  Cc. 
Crystallized  morphine  found  =  0.3087  Gm. 
=  11.32  Per  Cent. 
Experiment  JJ. — The  material  used  was  the  same,  but  the  method 
of  operation  differed  in  two  details.  (1)  Salicylic  acid  was  used  in 
larger  quantity  (2  Gm.  excess  instead  of  0.5  Gm.  previously  taken), 
and  (2)  the  volume  taken  of  the  filtrate  from  the  barium  sulphate 
was  only  45  Cc.  The  morphine  found  by  titration  thus  represented 
only  9/22  of  the  whole  amount  in  the  original  sample. 
Titration  Results. 
Total  acid  used  —  25.00  Cc. 
Acid  equivalent  to  the  alkali  =  15.58  Cc. 
Acid  equivalent  to  the  morphine  =  9.42  Cc. 
Crystallized  morphine  found  =  0.2826  Gm. 
or  .    =  1 1. 51  Per  Cent. 
Experiment  34. — This  determination  was  made  upon  material 
believed  to  be  of  Indian  origin.    The  method  used  and  quantities 
taken  were  the  same  as  in  Experiments  31  and  32.    The  determina 
tion  was  made  in  duplicate. 
