858                      Determination  of  Morphine.  { A%J°unI9PIgarm' 
Titration  Results. 
1.  11. 
Total  acid  used                                     ==  25.00  Cc.  25.00  Cc. 
Acid  equivalent  to  the  alkali                  =  14.71  Cc.  14.51  Cc. 
Acid  equivalent  to  the  morphine              =  10.29  Cc.  10.49  Cc. 
Corresponds  to  grammes  of  crystalline 
morphine 
or  crystalline  morphine  in  whole  11.32  Per  Cent.       11.54  Per  Cent. 
0.3087  0.3147 
Examination  of  Smoking  Opium.  Experiment  35. — The  material 
under  examination  was  smoking  opium  which  had  been  allowed 
partly  to  dry  in  the  air.  In  consequence  of  the  superficial  drying 
it  was  difficult  to  obtain  two  samples  which  were  true  duplicates. 
This  difficulty  was  overcome  by  taking  a  single  large  sample,  which 
was  weighed  into  a  tared  beaker,  dissolved  in  warm  water  and 
washed  into  a  graduated  (250  Cc.)  flask.  After  cooling,  150  Cc. 
of  cold  saturated  barium  hydroxide  solution  was  added,  and  the 
mixture  made  to  the  mark  with  cold  water.  It  was  allowed  to  stand 
20  minutes  and  filtered.  Two  portions  of  50  Cc.  each  were  taken 
from  the  filtrate,  and  the  analysis  of  each  was  continued  inde- 
pendently by  the  method  used  in  Experiment  31. 
Total  weight  of  opium  taken  =16.4180  Gm.  Weight  corre- 
sponding to  each  50  Cc.  of  alkaline  solution  =3.2836  Gm. 
Titration  Results. 
1.  11, 
Total  acid  used                                     =  25.00  Cc.  25.00  Cc. 
Acid  equivalent  to  the  alkali                   =  13.75  Cc.  13.85  Cc. 
Acid  equivalent  to  the  morphine             =  11.25  Cc.  11. 15  Cc. 
Corresponds  to  grammes  of  crystalline  ) 
,  .                                          [  0.3375  0.3345 
morphine  \ 
or  crytalline  morphine  in  whole  11.30  Per  Cent.       11.20  Per  Cent. 
A  determination  of  water  in  the  above  opium  was  subsequently 
made. 
Weight  of  moist  sample  2.31 16  Gm. 
Weight  of  dried  sample  1.9196G1T1. 
Weight  of  water  found  0.3920  Gm. 
The  above  corresponds  to  16.95  per  cent,  water,  which  is  con- 
siderably less  than  is  found  in  opium  freshly  prepared  for  smoking. 
From  the  above  results  the  mean  morphine  content  of  the  dry 
product  would  be  13.55  per  cent. 
