Am'juner'i9i8rin'  }  Advances  in  Pharmacy.  427 
Dichloramin-T  has  indeed  proved  itself  a  valuable  antiseptic  and 
now  that  the  ideal  solvent  has  been  found  its  uses  should  be  unlim- 
ited in  combating  bacterial  infection.  Splendid  clinical  results  have 
been  observed  with  the  5  per  cent,  solution  in  surgery  and  skin  dis- 
eases, with  the  2  per  cent,  solution  in  naso-pharynx  affections,  and 
with  the  0.5  per  cent,  solution  in  ophthalmology. 
McNeil  Laboratory, 
Philadelphia. 
QUARTERLY  REVIEW  OF  THE  ADVANCES  IN 
PHARMACY. 
By  John  K.  Thum,  Ph.M.,  Lankenau  Hospital,  Philadelphia,  Pa. 
In  the  Paris  letter  dated  March  28,  appearing  in  the  Journal  of 
the  American  Medical  Association,  May  4,  mention  is  made  of  a 
demonstration  by  Dr.  Bazin  at  the  Society  of  Biology  of  the  results 
of  comparative  experiments  between  the  antiseptic  power  of  the 
boric  acid-hypochlorite  mixture,  also  known  as  Vincent's  mixture, 
and  that  of  tincture  of  iodine  and  iodoform.  His  first  researches 
were  in  vitro  and  gave  evidence  that  to  inhibit  the  development  of 
bacteria  in  a  given  bouillon  culture  required  the  use  of  3  grams  of 
Vincent's  mixture,  while  to  check  the  cultures  in  the  same  bouillon, 
10  grams  of  tincture  of  iodine  and  25  grams  of  iodoform  were 
found  necessary.  In  order  to  determine  the  comparative  toxicity  of 
these  chemicals,  Dr.  Bazin  introduced  them  into  the  peritoneal  cavity 
of  guinea  pigs.  The  introduction  of  the  Vincent's  mixture  into 
the  cavity  caused  only  a  slight  reaction,  while  on  the  other  hand  the 
application  of  the  tincture  of  iodine  and  the  introduction  of  weak 
doses  of  the  iodoform  resulted  in  the  death  of  the  animals.  In  skin 
wounds  and  other  superficial  wounds  with  suppuration  after  infec- 
tion with  dirt,  the  tincture  of  iodine  and  the  Vincent's  mixture 
seemed  to  give  equal  results ;  in  wounds  of  the  muscles  soiled  with 
dirt  the  Vincent  mixture  exhibited  a  quite  noticeable  superiority. 
Investigation  also  showed  that  in  bone  wounds  the  mixture  was 
much  more  efficacious  than  the  tincture  of  iodine.  On  the  other 
hand  iodoform  showed  at  all  times  a  decided  inferiority. 
The  Pharmacology  of  Iodides. — Experimental  studies  were 
performed  on  the  absorption  of  iodides  from  the  digestive  tract,  their 
passage  to  the  blood,  and  consequent  elimination  with  the  urine. 
