Am'jlXi^8.rm"  }      The  New  Rem(?dies  of  ipif.  433 
cephaeline  causes  more  irritation  and  pain,  but  there  is  less  tendency 
to  diarrhoea  during  treatment.  The  dose  is  the  same  as  that  of 
emetine,  and  the  suggestion  is  that  a  combination  of  the  two  alka- 
loids would  be  more  efficient  than  emetine  alone. 
Halazone,  a  New  Water  Sterilizer. — The  problem  of  steriliz- 
ing water  for  troops  on  the  march  has  exercised  the  minds  of  those  in 
authority.  The  hypochlorite  method  is  useful  only  when  troops  are 
stationary.  Chloramine-T  requires  a  high  concentration  to  effect 
the  necessary  sterilization,  especially  with  hard  alkaline  waters,  and 
this  renders  the  water  unpalatable.  In  presence  of  an  acid,  such  as 
acetic  or  citric,  a  lower  concentration  is  effective,  but  chloramine-T 
decomposes  when  kept  in  contact  with  an  acid.  An  effective,  stable, 
and  inexpensive  agent  has  been  found  in  p-sulphondichlor-amino- 
benzoic  acid,  Cl2N.02S.C6H4.COOH,  one  part  of  which  in  300,000 
will  sterilize  highly  contaminated  water.  Tablets  containing  4  Mg. 
of  this  substance,  with  sodium  carbonate  and  sodium  chloride,  are 
used,  and  to  these  the  name  of  Halazone  has  been  given.  Halazone 
tablets  have  been  found  to  be  sufficiently  stable  for  all  practical  pur- 
poses.   One  tablet  is  usually  sufficient  to  sterilize  a  liter  of  water. 
Colloidal  Sulphur. — The  use  of  colloidal  sulphur  in  rheumatism 
is  on  the  increase,  and  as  the  preparation  can  easily  be  made  by 
any  pharmacist,  a  few  lines  may  be  devoted  to  this  subject.  The 
colloidal  sulphur  used  with  success  by  Major  Comrie  in  cases  of 
trench  rheumatism  is  prepared  as  follows:  Hydrochloric  acid  (10 
per  cent.  HQ),  22  Cc. ;  sodium  sulphide  (Na2S,  9H20),  5  Gm. ; 
sodium  sulphite  (Na2SOs,  7H.2O),  2.6  Gm. ;  white  of  two  eggs; 
sterilized  water  to  one  liter.  Dissolve  the  sodium  salts  separately, 
each  in  250  Cc.  of  the  water,  mix,  add  the  white  of  egg,  and  mix 
thoroughly.  Then  add  the  hydrochloric  acid,  diluted  with  250  Cc. 
of  the  water.  Mix,  warm  slightly,  and  make  up  to  one  liter  with 
sterile  water.  The  solution  is  dialyzed,  and  is  then  ready  for  use. 
The  strength  is  1  :  1,000,  and  the  commencing  dose  is  1  Cc,  in- 
creased to  2  Cc,  injected  into  the  painful  area  of  muscle,  the  point 
of  injection  being  slightly  varied  each  time.  An  injection  is  given 
every  second  day  for  three  weeks,  the  alternate  days  being  devoted 
to  massage  and  hot  alkaline  baths. 
Saccharin  in  Diet. — An  important  communication  by  Molliere  in 
La  Medecine  pratique  (July)  deals  with  the  use  of  saccharin.  He 
does  not  favor  its  too  free  use  in  the  replacement  of  sugar,  and 
