aju™^5?£"-}  Monobromated  Camphor.  201 
my  experiments.  Prof.  Maisch,  of  the  Philadelphia  College  of  Phar- 
macy, very  kindly  undertook  to  manufacture  it,  and,  overcoming  the 
great  difficulties  of  the  process,  succeeded  in  obtaining  it  in  beautiful 
crystals  free  from  the  slightest  yellow  tinge. 
My  experience  with  the  monobromated  camphor,  though  thus  far 
limited,  is  eminently  satisfactory.  I  have  employed  it  in  two  cases 
of  infantile  convulsions  due  to  the  irritation  of  teething,  with  the  ef- 
fect in  each  instance  of  preventing  the  further  occurrence  of  parox- 
ysms which,  previously  to  its  administration,  had  been  very  frequent. 
In  each  case  a  grain  was  given  every  hour,  rubbed  up  with  a  little 
mucilage  of  acacia.  Three  doses  were  sufficient  in  one,  and  two  in 
the  other  case.  The  children  were  aged  respectively  fifteen  and 
eighteen  months. 
In  a  very  obstinate  case  of  hysteria  occurring  in  a  young  married 
lady,  in  the  form  of  paroxysms  of  weeping  and  laughing,  alternating 
with  epileptiform  and  choreiform  convulsions,  I  gave  the  monobro- 
mated camphor  in  doses  of  four  grains  every  hour.  The  iufluence 
was  distinctly  perceived  after  two  doses  were  taken,  but  ten  were  ne- 
cessary to  entirely  break  up  the  attack.  This  was  a  very  favorable 
result,  as  all  previous  seizures  had  lasted  for  from  five  to  eleven  days, 
uninfluenced  by  medication  or  moral  suasion. 
I  have  also  employed  it  with  excellent  effect  in  several  cases  of 
headache  occurring  in  women  and  young  girls,  and  due  to  mental  ex- 
citement and  excessive  study.  One  dose  of  four  grains  was  gener- 
ally sufficient  to  cut  short  the  attack.  In  two  cases,  three  doses  at 
intervals  of  half  an  hour  were  necessary. 
In  wakefulness,  the  result  as  it  so  generally  is  of  cerebral  hypere- 
mia, the  monobromated  camphor  appears  to  be  greatly  inferior  to  the 
bromide  of  calcium  or  even  the  other  bromides.  But  it  is  apparently 
indicated  in  delirium  tremens.  I  have  not  yet  had  the  opportunity 
of  trying  it  in  this  disease,  but  I  should  not  hesitate  in  a  case  of  the 
affection  to  administer  it  in  doses  of  five  grains  every  hour  or  half- 
hour,  with  the  confident  expectation  that  sedation  and  sleep  would  re- 
sult. 
The  monobromated  camphor  may  be  given  in  the  form  of  pill,  with 
conserve  of  roses  as  the  excipient,  or  as  a  mixture  with  mucilage  of 
gum  arabic  and  syrup.  The  dose  for  adults  ranges  from  two  to  five 
grains. — New'  York  Medical  Journal,  May,  1872. 
