302 
PREPARATIONS OP MANGANESE. 
lozenges. The pills contain each three grains of phosphate 
and one of Peruvian bark, made into form with syrup of 
catechu. 
Malate of Manganese is recommended as one of the best 
preparations of this metal for medical use. It is made by 
saturating a solution of malic acid with carbonate of man- 
ganese. The scarcity of the acid renders this salt too ex- 
pensive for general use; but should it really merit the pre- 
ference to others more readily attainable, and be in demand, 
the following is, perhaps, the most eligible process. The 
malic acid is derived from sumac berries (Rhus glabrum) 
as recommended by Prof. W. B. Rogers ( Amer. Jour.Pharm., 
vol. 7 p. 56 ;) the red exterior coating of which contains 
a considerable amount of bi-malate of lime. 
The berries, deprived of their supporting peduncles, are 
infused in boiling water, without bruising, until the acid 
salt is dissolved out. The infusion is filtered through cotton 
flannel, evaporated to a syrupy consistence, and set aside to 
crystallize. The bi-malate of lime readily separates in 
regular crystals: these are drained, dissolved in a small 
quantity of boiling water, and again crystallized by cooling. 
The bi-malate is redissolved in the smallest possible quanti- 
ty of boiling water, and diluted sulphuric acid dropped in 
carefully, until it ceases to produce a precipitate. Allow 
the solution of malic acid to cool, separate the precipitated 
sulphate of lime by a filter, and wash out the malic acid 
which adheres to it with a little water. Lastly, satu- 
rate the solution of malic acid with carbonate of manga- 
nese, filter and evaporate carefully by a water bath. 
M. Hannon recommends malate of manganese in the 
forms of syrup, pills, and lozenges. The syrup is made by 
dissolving one ounce of the salt in a pint of simple syrup. 
He also remarks, that " the preparations of manganese have 
this immense advantage over those of iron, that they can 
be combined with vegetable tonics and astringents, viz : 
tannin, and the substances which contain it; as gall-nuts, 
rhatany, catechu, dragon's blood, kino, monesia, cinnamon, 
