CHANGE OP CALOMEL. 
167 
indications in the above diseases. That it may have this ten- 
dency, will be obvious in considering the reactions which will 
be consequent on the mixture of these two ingredients. The 
meconic acid of the bimeconate of morphia would first neu- 
tralize any excess of oxide of lead in the acetate, and then the 
remainder would unite with more of the lead, and liberate ace- 
tic acid, thus forming an insoluble meconate of lead, which 
would pass through the intestines and be discharged. This 
remedy, however, is not employed to the same extent here in 
chronic cases, where a long continued use is required to pro- 
duce its full effect, as it is in Germany. In this latter country 
it is very highly recommended in consumptive affections, and 
effects may result from its prolonged use, which would not ap- 
pear from a greater amount of the remedy given in a much 
shorter time. R. B. 
ART. XXIX. — ON THE TRANSFORMATION OF CALOMEL IN- 
TO CORROSIVE SUBLIMATE. By M. Mialhe. 
I have the honor to communicate to the Society of Phar- 
macy, the summary of some experiments which I have made 
on the transformation of calomel into corrosive sublimate, ex- 
periments which I was suddenly forced to interrupt. 
The point from which I started with my researches, was 
the following fact, reported by Vogel. A physician pre- 
scribed for a child twelve papers, each containing five 
grains of sal ammoniac, five grains of sugar, and half a grain 
of calomel : the child having died after taking several of the 
powders, the apothecary was accused of having committed an 
error in compounding the prescription. Luckily for our col- 
league, the accusation which hung over him was of short du- 
ration, Peter Koffer having quickly proven that, in presence 
