MISCELLANY. 
351 
with good effects. But as this is a salt subject to decomposition, Signor 
Bertozzi of Cremona, has proposed to substitute the hydrocyanoferrate of 
quinine, the powers of which over the worst forms of intermittent fever 
have been completely established. 
Dr. Zaccarelli has prescribed this new medicine in a great number of 
cases in place of sulphate of quinine. It is found to cut short tertian and 
quartan fevers; and, what is well worthy of the attention of physicians, 
it has principally succeeded in cases where the sulphate of quinine has 
failed. Dr. Carioli has also confirmed the febrifuge properties of this pre 
paration. 
The following is given by Bertozzi as the most economical process for 
obtaining it. One part of sulphate of quinine is to be tritujrated in a glass 
mortar to an impalpable powder; a part and a half of the ferro-prussiate 
of potash, previously dissolved in six or seven parts of distilled water, is 
to be mixed by careful agitation, and the whole exposed in a flask to heat, 
stirring the mixture carefully until it arrives at the boiling point. In pro- 
portion as the liquid becomes transparent, there is precipitated to the bot- 
tom and sides of the flask a substance of a greenish-yellow color, having 
an oily consistence. Having poured off the liquid portion, this substance 
is to be washed with distilled water, and then dissolved in very pure alco- 
hol at 100° Fahr., and immediately filtered. On evaporating the alcohol, 
a mass, confusedly crystallized in needles, is left, the weight of which 
amounts to three-fourths of the sulphate of quinine used. This is the hy- 
drocyanoferrate of quinine. 
When in small fragments this substance is of a pea-green color, and of 
an intensely bitter taste. It dissolves in cold, but better in hot alcohol 
and is precipitated from its solution almost entirely by water. It is decom- 
posed by sulphuric acid, and by the tincture, infusion, and decoction of 
cinchona. It has been given in doses of three grains and a half, repeated 
as occasion required. 
Ibid., from Dublin Journ. Med. Sci. July, 1840. 
Tunic Astringent Pills of Which. — The following is the formula for these 
pills: — R. Terebinth, Venet. Extr. Gentian, aa gij ; Ferri Sulphat. Kino 
aa 31SS.M. To be made into pills of a grain and a half each. These pills 
are said to be very efficacious in the cure of gonorrhoea and of chronic leu- 
corrhrea. The dose is four pills three or four times a day. 
Ibid,, from Journ. des Connaiss. Med. Prat, et de Pharm., June, 1840. 
Action of Albumen on Corrosive Sublimate. — The change induced by al- 
bumen on corrosive sublimate when taken internally, is one of the most 
interesting problems in chemistry. It is universally considered as an an- 
tidote if taken sufficiently early, but how it acts seems at present to be a 
matter in doubt. I believe Dr. Bostock was one of the first who noticed 
