A^uiyimA4RM"}         Cephalanthus  Occidentalis.  313 
of  resin  was  deposited  and  then  the  solution  became  clear  again,  but 
on  addition  of  more  water,  the  same  result  was  obtained,  until  quite 
a  quantity  of  water  had  been  added. 
The  resinous  residue  was  of  a  light-brown  color,  and  on  being 
treated  with  ether,  about  one-third  was  taken  up  and  gave  a  soft 
residue  of  yellow  color. 
The  alcoholic  resin  on  the  removal  of  this  lighter- colored  resin  be- 
came dark-brown,  granular,  and  left  a  lasting  bitterness  in  the  fauces. 
It  was  insoluble  in  chloroform  and  benzin,  soluble  in  alkaline  solu- 
tions. A  portion  dissolved  in  solution  of  potassa  was  precipitated  by 
HC1 ;  also  by  solution  of  cupric  sulphate,  insoluble  in  excess  of 
potassa.  On  boiling  another  portion  with  dilute  H2S04,  it  was  proven 
to  be  a  glucoside,  giving  glucose  and  a  light-brown  powder  as  the 
other  product.  This  resin  was  considered  identical  with  the  glucoside 
obtained  from  the  neutral  acetate  of  lead  precipitate.  The  drug 
being  laxative  with  presence  of  the  tannin,  it  was  supposed  this  resin 
might  possess  purgative  properties.  Five  grains  were  taken,  but  no 
result  realized. 
The  ethereal  resin  on  being  treated  with  benzin,  was  deprived  of  a 
fatty  substance,  leaving  a  granular  residue  with  bitter  taste,  an  acid 
reaction,  and  perfectly  soluble  in  chloroform. 
The  aqueous  solution  from  the  alcoholic  extract  on  being  agitated, 
considerable  froth  was  formed,  which  remained  permanent,  in  this 
respect  corresponding  with  saponin,  but  solution  of  baryta  produced 
no  precipitate.  The  solution  was  concentrated,  boiled  with  oxide  of 
lead,  filtered  and  the  excess  of  lead  removed  by  H2S.  It  was  then 
heated,  filtered  and  evaporated  to  a  very  concentrated  state.  In 
this  the  frothing  principle  was  still  retained ;  alcohol  added  to  this  to 
preserve  the  solution,  caused  a  copious  light-colored  deposit.  The 
precipitate  was  collected,  and  on  drying,  became  almost  black ;  it  had 
a  slight  bitter  taste  at  first,  but  it  was  not  lasting  ;  was  neutral  to 
test  paper,  and  on  agitation  with  water  was  partially  dissolved,  caus- 
ing quite  a  foam.  On  evaporating  the  filtrate,  from  which  this  prin- 
ciple was  obtained,  it  was  found  to  contain  glucose  and  an  intensely 
bitter  principle,  as  did  the  filtrate  from  the  decoction  treated  with 
lead  before  digesting  with  charcoal.  This,  on  agitation  with  water, 
still  frothed,  but  not  to  the  extent  of  the  precipitate. 
A  concentrated  solution  of  aqueous  extract  obtained,  as  before  stated, 
from  the  dregs  after  exhausting  the  drug  with  alcohol,  was  treated 
