358  Emulsionizing  Hoffmanns  Anodyne.  {A\^Tj8n74RM' 
color,  and  a  bitter  and  astringent  taste  ;  was  but  slightly  soluble  in 
water,  ether  and  chloroform,  imparting  merely  a  light-green  color  to 
the  latter  solutions.  It  consisted  of  resin,  chlorophyll,  bitter  extrac- 
tive and  coloring  matter. 
The  extract  obtained  from  the  etherial  tincture  was  of  a  dark-green 
color,  and  of  an  agreeable  aromatic  odor,  but  of  exceedingly  disagree- 
able taste,  resembling  somewhat  that  of  coal  oil.  This  extract  was 
insoluble  in  water,  but  readily  soluble  in  alcohol  and  bisulphide  car- 
bon, and  sparingly  so  in  chloroform.  It  consisted  mainly  of  chloro- 
phyll, waxy  matter  and  an  acrid  resin. 
A  portion  of  the  herb  was  distilled  with  water,  but  no  indications 
of  a  volatile  oil  were  obtained. 
From  the  foregoing  experiments  I  would  infer  that  the  medicinal 
properties  of  frostwort  are  due  to  tannin  and  extractive  matter. 
The  constituents  of  frostwort  may  be  briefly  summed  up  as  follows  : 
Tannin,  of  which  it  contains  a  large  percentage,  resin,  glucose,  gum, 
extractive  matter,  chlorophyll  and  inorganic  salts. 
EMULSIONIZING  HOFFMANN'S  ANODYNE. 
Editor  American  Journal  of  Pharmacy  : 
A  few  days  ago,  I  received  the  following  prescription  : 
Hoffmann's  anodyne,        ....  ^ii, 
Acacias  pulv.,  .... 
Sacchar.  alb.,       ....  aa  gii, 
Aquae,  .....  ^i. 
Never  before  having  had  to  make  a  similar  mixture,  I  had  my 
doubts  about  its  feasibility  ;  at  any  rate,  I  would  try.  The  old  mor- 
tar process  having  failed  (not  to  mention  that  no  inconsiderable  part 
of  the  anodyne  volatilizes  before  the  mixing  can  be  done),  I  tried  the 
bottle  process  of  Mr.  Forbes  {Am.  Journ.  Pharm.,  1872,  p.  61).  For 
some  reason  or  other,  I  did  not  succeed,  probably  for  want  of  dex- 
terity. Mr.  Forbes'  process  is  first  to  put  the  liquid  to  be  emulsion- 
ized  m  the  bottle,  then  a  small  quantity  of  powdered  gum,  shaking 
well,  and  then  water. 
At  last  I  hit  upon  the  following  : 
I  put  in  the  bottle — 
Mucilag.  acac.  (U.  S.  P.).  .... 
Water,  .  .  .  •  '  f3vi, 
Hoffmann's  anodyne,         ....  f^ii, 
