As™ptJembe?,hia89™"}    American  Pharmaceutical  Association.  513 
chemical  workers  into  their  laboratories  that  the  manufacturers  of  Ger- 
many do. 
The  next  subject  to  which  the  attention  of  the  audience  was  called  was  that  of 
the  methods  of  study  and  research  which  the  modern  worker  in  scientific  phar- 
macy should  follow.  The  difference  in  the  amount  of  scientific  study  de- 
manded twenty-five  or  thirty  years  ago  and  at  the  present  time  was  dwelt  upon, 
and  the  reason  for  the  increase  was  declared  to  be  two-fold.  "A  wider  range 
of  studies  must  be  covered,  owing  to  the  broader  demands  which  modern  society 
makes  of  her  educated  citizens,  and  the  interdependence  of  the  several  branches 
of  science  constantly  becoming  greater.  The  field  before  the  scientific  student 
of  pharmacy  has  broadened,  the  methods  of  study  have  become  more  diversi- 
fied, and  the  resources  and  facilities  of  our  schools  have  been  correspondingly 
increased.  If  we  are  as  interested  in  the  advance  of  pharmacy  as  we  claim  to 
be,  let  us  not  fail  to  be  equal  to  our  opportunities." 
"To  this  end,  the  action  taken  last  year,  at  the  suggestion  of  my  predecessor 
in  this  chair,  of  forming  a  Committee  of  Research  would  seem  to  be  eminently 
proper.  It  has  not  yet,  however,  been  productive  of  very  extensive  results. 
Possibly  if  the  Committee  were  made  larger  and  more  representative,  including 
more  of  the  centres  of  pharmaceutical  research,  it  might  be  made  to  accom- 
plish more.  While  I  make  no  recommendations  on  this  subject,  it  is  a  matter 
which  could  well  occupy  the  attention  of  the  Section  at  one  of  its  sessions. 
By  a  free  interchange  of  opinion  we  could  learn  how  to  best  stimulate  the 
activity  of  all  interested  in  this  most  desirable  work." 
The  address  was  received  and  referred  for  publication.  The  Chairman  then 
called  for  reports  of  committees.  The  committee  appointed  at  Asheville, 
1894,  and  continued  at  Denver  last  year,  to  investigate  the  question  of  indi- 
cators in  the  titration  of  alkaloids,  submitted  its  report  through  Chairman 
Kebler.  The  committee  had  secured  the  continued  services  of  Professor 
Lloyd,  of  Cincinnati,  the  assistance  of  Professor  Bennett,  of  Ames,  la.,  and  of 
Professor  Base  and  Dr.  Bngelhardt,  of  Baltimore.  Brazil  wood,  cochineal, 
hematoxylin,  lacmoid,  tropseolin  OO,  and  iodo-eosin  were  investigated  in  this 
connection.  Considerable  difficulty  was  experienced  in  securing  some  of  the 
indicators  of  a  satisfactory  quality.  This  was  especially  true  of  tropaeolin  OO 
and  iodo-eosin.  Of  the  former  none  was  secured  satisfactorily  sensitive,  in  the 
Chairman's  opinion,  but  another  member  of  the  committee  considered  one 
sample  satisfactory.  Only  one  sample  of  iodo-eosin  was  obtained.  All  of  the 
materials  to  be  operated  on,  including  the  indicators,  were  sent  to  each  worker, 
Accompanying  the  materials  were  instructions  in  detail  for  the  preparation  of 
the  solutions  of  the  indicators,  regarding  the  amount  of  each  solution  to  be 
used  per  titration,  for  the  standardization  of  the  volumetric  solutions  of  sulphuric 
and  hydrochloric  acids  and  potassium  hydroxide,  and  for  operating  on  samples  of 
quinine,  cinchonine,  strychnine,  brucine,  morphine,  atropine,  fluid  extract  of 
coca  leaves,  and  powdered  nux  vomica  and  coca  leaves.  For  the  fluid  extract 
and  powders  the  following  methods  were  prescribed  : 
Fluid  Extract  of  Coca  Leaves. — Ten  grammes  of  the  fluid  extract  are 
diluted  with  10  grammes  of  distilled  water  in  a  250  c.c.  flask,  25  grammes  of 
chloroform  and  75  grammes  of  ether  added,  the  vessel  securely  stoppered  and 
well  agitated.  Add  5  grammes  of  10  per  cent,  ammonia  water  and  agitate  the 
mixture  frequently  during  half  an  hour. 
