544 
Oil  of  Monarda  Fistulosa. 
/Am.  Jour.  Pharm. 
\    October,  18<6. 
No.  of  Oil. 
By  Titration. 
Per  Cent. 
52-00) 
By  Volume. 
Per  Cent. 
Percentage 
by  Volume 
in  ioo-c  c.  Cylinder, 
Per  Cent. 
64*0 
66 -o 
70-0  1 
ro  J 
65'2 
67  6 
64-5 
65"5 
72  o 
64-4 
(2)  52-30/ 
f  (1)  547o) 
1(2)  54'ooi 
f(i)  58-48^ 
(2)  58-00/ 
(1)  53'20| 
(2)  53"4oj 
f(i)  53"34\ 
J  (2)  53-36/ 
10  \  .  -\ 
(1)  54-46  ) 
1  (2)  54-26/ 
Isolation  of  CarvacroL — The  aqueous  alkaline  solution  containing 
the  sodium  carvacrolate  was  distilled  with  water  vapor  to  remove 
any  dissolved  non-phenol  portions  of  the  oil.  The  solution  was 
then  acidulated  with  50  per  cent,  sulphuric  acid,  and  again  distilled 
and  identified  as  carvacrol  iodide,  into  which  all  of  it  was  converted. 
In  the  flask  there  remained  a  dark  brown,  tarry  residue.  An  at- 
tempt to  sublime  this  between  watch-glasses  proved  a  failure. 
Non-Phenols. — The  combined  portions  of  non-phenols  from  the 
various  oils  were  distilled  with  water  vapor.  The  first  portion  came 
over  very  clear,  and  then  a  much  darker  portion.  These  were  kept 
separate.  The  light  portion  had  a  specific  gravity  of  0-847  at  2I°C, 
and  rotatory  power  of  24/  in  22°  mm.  tube.  The  dark  portion  had 
a  specific  gravity  of 0-874  at  210  C,  and  rotatory  power  of —  70  50' 
in  220  mm.  tube. 
In  order  to  ascertain  the  presence  or  absence  of  esters  in  this  por- 
tion of  the  oil,  the  following  ester  determinations  were  made  : 
Ten  c.c.  of  the  light  portion  were  boiled  for  one  hour  with  50  c.c. 
of  a  50  per  cent,  alcoholic  potassium  hydroxide  solution.  Upon 
titration  of  the  alkali  it  was  found  that  no  saponification  had  taken 
place.  The  same  experiment  was  tried  with  the  dark  portion  with 
like  results. 
The  light  and  heavier  oils  were  then  fractionated  separately,  the 
results  of  the  fractionations  being  recorded  in  the  following  table : 
.  3  Burette  reading.    For  further  details,  see  "The  Volumetric  Estimations  of 
Phenols,"  by  Edward  Kremers  and  O.  Schreiner. 
4  Taken  for  comparison  from  the  first  table. 
