ANd%imbe?,hiab9™*}  Antimonii  Oxidum  and  Pulvis  Antimonialis.  597 
Miss  Ellen  G.  Jenners,  and  one  son,  George  B.  Markoe,  now  in 
Colorado  Springs,  Col.,  was  the  fruit  of  this  union.  Mrs.  Markoe 
died  in  1 879,  after  a  lingering  illness,  and  in  1 881  he  was  again 
married,  this  time  to  an  English  lady,  Miss  Louise  E.  Moore. 
His  widow  and  a  daughter,  born  in  1893,  survive  him. 
Undoubtedly,  Professor  Markoe  possessed  the  qualifications  for  a 
great  leader,  but  was  handicapped  by  the  meagreness  of  his  early 
education.  In  spite  of  this,  he  lived  to  see  a  struggling  college, 
which  he  was  the  immediate  means  of  starting,  grow  into  a  strong 
and  influential  institution,  and  himself  publicly  honored  for  his 
scholarship. 
He  could  not  help  feeling  that  in  the  changes  of  the  past  twenty- 
five  years  he  had  no  small  part,  and  he  derived  a  genuine,  albeit  a 
modest,  satisfaction  therefrom.  His  life  is  a  worthy  example  for  the 
youth  of  small  opportunities,  and  should  be  an  incentive  to  re- 
doubled efforts  for  the  strengthening  of  the  ideal  in  pharmacy. 
ANTIMONII  OXIDUM  AND  PULVIS  ANTIMONIALIS. 
By  Charges  H.  IvaWaix. 
Antimony  trioxide,  Antimonii  Oxidum,  U.  S.  P.,  1890,  was 
admitted  to  the  Pharmacopoeia  of  the  United  States  in  i860,  at 
which  time  it  was  included  in  the  secondary  list,  comprising  the 
preparations,  as  a  process  was  given  for  its  manufacture.  The  edi- 
tion of  1870,  of  the  same  work,  retained  it  in  the  same  class  ;  but 
in  the  revision  of  1880,  at  which  time  the  distinction  between  pri- 
mary and  secondary  classes  was  abandoned,  it  was  included  among 
the  compounds  of  antimony,  the  process  for  preparing  it  being 
omitted.    The  present  edition  made  no  further  change. 
The  commercial  article  is  used  in  the  arts  as  a  pigment,  but  has 
never  occupied  an  important  position  in  medicine,  and  few  retail 
pharmacies  even  have  it  in  stock.  It  enters  into  the  composition  of 
antimonial  or  James'  powder,  Pulvis  Antimonialis,  U.  S.  P.,  and,  in 
the  earlier  editions  of  the  Pharmacopoeia,  it  was  used  in  the  prepa- 
ration of  tartar  emetic.  The  manufacture  of  this  compound  has 
long  since  been  discontinued  by  retail  pharmacists,  the  present  ten- 
dency of  pharmacy,  regarding  chemicals,  being  more  toward  analyti- 
cal than  manufacturing  work. 
