Am.  Jour.  Pharm.\ 
Sept.,  1885.  J 
Sanguinarine  and  Chelidonine. 
453 
of  the  alkaloid  a  solution  of  iodo-potassium  iodide  gives  a  deep  brown 
flocculent  precipitate.  Vanadio-sulphuric  acid  gives  a  beautiful  rose-red 
color  which  slowly  disappears.  A  crystal  of  potassium  dichi'omate  and 
sulphuric  acid  give  a  golden-yellow  color,  changing  to  brown  and  green. 
Chlorine- water  gives  no  coloration,  even  in  the  presence  of  hydrochloric 
acid.  Bromine-water  added  to  a  solution  of  hydrastine  in  strong  sul- 
phuric acid  gives  an  immediate  orange  precipitate.  Hydrastine  is 
insoluble  in  light  petroleum,  but  the  greater  part  dissolves  in  benzene. 
Oxyacanthine  gives  white  precipitates  with  potassio-mercuric  iodide, 
tannic  acid,  and  potassio-cadmium  iodide ;  orange  precipitates  with 
picric  acid  or  potassio-bismuthic  iodide,  and  a  deep  brown  precipitate 
with  iodo-potassium  iodide.  Molybdic  and  sulphuric  acids  give  an 
immediate  violet  coloration,  changing  to  yellowish-green  at  the  edges. 
Oxyacanthine  is  not  extracted  from  acid  solutions  by  light  petroleum 
or  benzene,  and  only  sparingly  by  chloroform. — Jou7\  Chem.  SoG.y 
May,  1885,  p.  606  ;  Zeit.  Anal.  Chem.,  vol.  24,  157-163. 
DETECTION  OF  SANGUINARINE  AND  CHELIDONINE. 
By  a.  v.  Kugelgen. 
Concentrated  sulphuric  acid  gives  with  0*1  mgrm.  of  sanguinarine 
a  blue-violet  coloration,  changing  after  several  hours  to  a  dirty  green. 
Sulphuric  and  molybdic  acids  give  a  violet  color  with  a  tinge  of  red 
resembling,  but  somewhat  lighter  than,  the  corresponding  morphine 
reaction  ;  after  an  hour,  the  color  becomes  brown  and  eventually  green. 
Vanadium  sulphate  gives  a  bluish-violet  color,  which  turns  bluish- 
black  on  standing.  Selenic  and  sulphuric  acids  do  not  give  so  intense 
a  violet  color  as  is  produced  when  sulphuric  acid  alone  is  added. 
0'02  mgrm.  of  the  alkaloid  in  a  few  drops  of  dilute  sulphuric  acid 
(1  of  acid  to  50  of  water)  gives  precipitates  with  tannin,  bromo-potas- 
sium  bromide,  phosphotungstic  acid,  iodo-potassium  iodide,  and  phos- 
phomolybdic  acid ;  and  a  turbidity  with  picric  acid,  potassio-mercuric 
iodide,  potassio-cadmium  iodide,  potassio-bismuthic  iodide,  and  gold 
chloride.  Sanguinarine  is  not  extracted  from  its  acid  solutions  by 
light  petroleum,  and  only  sparingly  by  benzene  and  chloroform. 
Chelidonine. — 0'5  mgrm.  of  this  alkaloid  gives  with  sulphuric  acid 
at  first  a  pale-green  color,  changing  to  brown  edged  with  red  or  violet. 
The  violet  color  is  only  observed  in  strong  solutions.    Sulphuric  and 
