Am.  Jour.  Pharm.) 
Sept.,  1885.  j 
Gleanings  in  Materia  Medica. 
457 
filtrate  determined  by  titration  with  uranium  acetate.  The  fat  was 
extracted  from  the  fine  powder  by  petroleum  benzin,  and  this  exhausted 
powder  used  for  determining  the  caffeine,  which  had  to  be  freed  from 
traces  of  fat  by  benzin.  Nitrogen  was  estimated  by  the  method  of 
Dumas,  as  modified  by  Zullkowsky  and  Arzberger;  after  deducting 
the  nitrogen  of  the  caffeine,  the  remainder  multiplied  by  Q,  gave  the 
albuminoids.  For  the  determination  of  tannin  a  modification  of 
LdwenthaFs  method  was  used  and  the  permanganate  solution 
standardized  with  pure  coffeotannic  acid.  The  cellulose  was  found 
according  to  F.  Schulze  by  successive  treatment  with  nitric  acid  sp.  gr. 
water,  diluted  ammonia,  alcohol  and  ether.  The  following 
results  were  obtained  : 
Moisture. 
Ash., 
1 
Phosphoric 
Acid. 
Nitrogen, 
total. 
Albuminoids. 
Caffeine. 
- 
Fixed  Oil. 
Tannin. 
Cellulose, 
11-16 
3-54 
•402 
4^14 
22^95 
1-09 
13-50 
6-50 
11-59 
Highest  
12-72 
4'2i 
-490 
4^46 
24-78 
1-22 
16-48 
7-60 
13-03 
8-66 
2-92 
•280 
S-6B 
19-86 
0-99 
11-26 
5-46 
8-68 
— Phar.  Zeitschr.  RussLy  1885. 
Cupreol  and  Cinchol  are  isomeric  compounds  of  the  formula 
C20H34O,  which  were  isolated  by  O.  Hesse,  the  former  from  cuprea 
bark,  the  latter  from  different  cinchona  barks  ;  in  addition  to  cinchol 
the  bark  of  C.  Ledgeriana  contains  also  the  isomeric  quebrachol.  These 
three  compounds  as  well  as  phytosterin,  isolated  by  Hesse  from  Calabar 
beans  and  from  peas,  belong  to  the  class  of  cholesterins.  The  above 
new  compounds  were  prepared  from  the  coarsely  powdered  barks  (20 
to  25  kilos  being  used)  by  exhausting  with  petroleum  benzin^  treating 
the  extract  with  boiling  alcohol,  cooling  to  separate  greenish  resin, 
concentrating  between  40°  and  60°  C.  until  resin  began  to  separate, 
then  evaporating  the  clear  liquid  spontaneously,  and  separating  the 
oily  matter  by  means  of  bibulous  paper  or  by  saponification  with 
potassa.  From  0*002  to  0'003  per  cent,  of  cupreol  was  obtained  from 
cuprea  bark,  and  it  was  also  found  besides  cinchol,  in  the  bark  of 
Cinch,  officinalis  and  C.  Calisaya  var.  Schuhkraflft. 
Cupreol  crystallizes  from  alcohol  or  glacial  acetic  acid  in  colorless 
