Am.  Jour.  Pharm.  ) 
January,  1920.  ) 
Current  Literature. 
6i 
tension  and  chronic  nephritis  there  is  but  an  occasional  trace  of 
sugar  in  the  urine  and  the  blood  sugar  is  not  unduly  high,  then, 
Hamman  says,  the  disordered  carbohydrate  metabolism  must  be 
subordinated  to  the  renal  or  vascular  condition.  If  there  is  marked 
glycosuria  and  the  blood  sugar  is  unusually  high,  then  the  diabetes 
must  be  emphasized.  The  clinical  history  is  of  importance. 
Patients  past  middle  life  with  mild  diabetes  often  gradually  de- 
velop nephritis  and  hypertension,  so  that  finally  the  renal  and  vascu- 
lar conditions  assume  the  prominent  position  in  the  clinical  pic- 
ture. On  the  other  hand,  Hamman  has  observed  patients  with 
hypertension  over  a  number  of  years  and  has  seen  them  gradually 
develop  glycosuria  and  finally  a  definite  intolerance  for  carbohy- 
drates. {Canadian  Med.  Assoc.  Jour.;  through  Jour.  Amer.  Med. 
Assoc.,  December  6,  1919.) 
Use  of  Platinum  Cklorid  in  Pneumonia. — Anklesaria  has  made 
use  of  a  o .  I  per  cent,  solution  of  platinum  chlorid  in  5  minim  doses, 
in  combination  with  Burney  Yeo's  effervescent  quinine  mixture, 
every  four  to  six  hours,  in  the  treatment  of  pneumonia.  He  claims 
to  have  had  very  good  results.  The  effect  in  some  instances  was 
really  very  striking.  Within  twelve  hours  of  the  treatment  a  notice- 
able change  for  the  better  was  observed.  He  has  also  used  quinine 
in  a  somewhat  different  form  and  manner.  An  ounce  of  good 
quinine  is  well  rubbed  with  an  equal  quantity  of  powdered  carbonate 
of  ammonia.  The  powder  is  then  made  into  a  paste  with  an  ounce 
of  liquor  ammoniac  and  set  aside  for  an  hour.  Absolute  alcohol, 
4  ounces,  is  now  added  to  the  paste  and  the  solution  is  filtered. 
The  filtrate  thus  obtained  is  added  to  a  pound  of  aromatic  spirits 
of  ammonia  (B.P.).  The  clear  mixture  is  labeled  mixture  of  quinine 
carbonate,  i  :  20.    It  is  prescribed  as  follows: 
Gm.  or  Cc. 
Sodii  bicarbonatis  
Mist,  quininea  carbonatis  
Vini  ipecacuanhae  
Syrup  aurantii  
Aquae  anisi  q.  s.  ad. .  .  . 
M  Ft.  misturam. 
Sig.    One  ounce  every  four  to  six  hours. 
24 
80 
2 
4 
8 
3  J 
3  ij 
3  SB 
3  V j 
B  vj 
To  the  mixture  for  an  adult,  10  minims  of  a  i  :  1,000  platinum 
chlorid  solution  are  added  on  the  first  day,  7.5  minims  on  the  second 
