Am.  Jour.  Pharm. 
May,  1920. 
Pharmacology  of  Cotton  Root  Bark. 
299 
Experi- 
ment or 
Kymo.  Drug 
1         Pituitary  Extract 
Alcohol 
(( 
Pituitary  Extract 
Table  7 
Isolated  Uterus  Experiments 
Guinea  Pig's  Uterus 
Commercial  Drug 
Dilution 
300,000 
1,333 
1,333 
300,000 
Effect 
85  m.m 
21  " 
17 
67 
(Contractions  ,etc.) 
contraction 
Pituitary  Extract 
Alcohol 
u 
Pituitary  Extract 
300,000 
1,333 
1,333 
300,000 
87 
53 
45 
92 
3E*     Alcohol  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
Alcohol  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
Alcohol  1 
1,333 
1,000 
1,333 
1,000 
1,000 
lU  m.m. 
38 
20  " 
48 
22  " 
contraction 
Pituitary  Extract 
Alcohol-glycerine,  3-1 
u  "  u 
F.  E.  Cotton  R.  B.  (N.  F.) 
F.  E.  Ergot 
250,000 
100 
1,000 
1,000 
5,000 
27    mm.  contraction 
Relaxation  (slight) 
No  noticeable  effect 
mm. 
contraction 
Pituitary  Extract  1 
Alcohol-glycerin,  3-1  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
F.  E.  Ergot  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
F.  E.  Ergot  1 
300,000  26    mm,  contraction 
1,000  No  noticeable  effect 
1,000  2    mm.  contraction 
5,000  4 
1,000  No  noticeable  effect 
5,000  3.5  mm.  contraction 
6D      Pituitary  Extract 
u     "  u 
F.  E.  Cotton  R.  B.  (N.  F.) 
F.  E.  Ergot 
250,000 
250,000 
1,000 
4,000 
24 
21 
1.5 
24 
mm. 
contraction 
7C  Pituitary  Extract  1 
F.  E.  Cottou  R.  B.  (N.  F.)  1 
F.  E.  Ergot  ^1 
250,000 
1,000 
10,000 
87  mm. 
14 
70 
contraction 
8B  Pituitary  Extract  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
F.  E.  Ergot  1 
200,000 
500 
5,000 
33  mm. 
9 
24 
contraction 
Pituitary  Extract 
F.  E.  Cotton  R.  B.  (N.  F.) 
300,000 
500 
107  mm. 
55 
contraction 
lOG  F.  E.  Ergot  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
F.  E.  Ergot  1 
10,000 
1,000 
10,000 
48  mm. 
26 
43 
contraction 
11  Pituitary  Extract  1 
F.  E.  Cotton  R.  B.  (N.  F.)  1 
Pituitary  Extract^  1 
300,000 
133 
300,000 
122  mm. 
115 
123  " 
contraction 
12F      Pituitary  Extract 
F.  E.  Cotton  R.  B.  (N.  F.) 
Pituitary  Extract 
F.  E.  Ergot 
Pituitary  Extract 
F.  E.  Cotton  R.  B.  (N.  F.) 
u 
F.  E.  Ergot 
F.  E.  Cotton  R.  B.  (N.  F.) 
250,000 
1,000 
250,000 
10,000 
250,000 
1,000 
1,000 
10,000 
10,000 
10,000 
10,000 
1,000 
30  mm. 
6 
11 
21 
73 
6 
4 
5 
5 
10 
31 
22 
contraction 
