300 
Pharmacology  of  Cotton  Root  Bark. 
Am.  Jour.  Pharm. 
May,  1920. 
Experi- 
ment or 
Kymo. 
13 
Table  7 
Isolated  Uterus  Experiments 
Guinea  Pig^s  Uterus 
Commercial  Drug 
Drug 
Pituitary  Extract 
Alcohol 
Pituitary  Extract 
F.  E.  Cotton  R.  B.  (N.  F.) 
Pituitary  Extract 
Dilution  Effect 
300,000      5:  m 
1,333 
1,000 
1,333 
300.000 
1,000 
1,000 
1,000 
300,000 
300,000 
16 
13 
10 
42 
14 
13 
4 
6 
7 
(Contractions,  etc.) 
contraction 
fH.T. 
H.T. 
H.T. 
L.T. 
L.T. 
L.T. 
L.T. 
L.T. 
tH.  T.  =  Higher  Tonus.   L.  T.  =  Lower  Tonus. 
14         Pituitary  Extract 
1 
250,000 
14  mm. 
contraction 
1 
250,000 
13.5 
a 
u 
Alcohol 
1 
1,333 
0 
u 
u 
11 
1 
1,333 
1 
u 
u 
1 
1,333 
1 
(I 
u 
(I 
1 
1.333 
1  (?) 
u 
Pituitary  Extract 
1 
250,000 
30 
« 
u 
1 
240,000 
32 
« 
il 
F.  E.  Cotton  R.  B.  (N.  F.) 
1 
1,000 
5 
u 
u 
1 
1,000 
4 
u 
u 
(( 
1 
1,000 
2 
u 
u 
Pituitary  Extract 
1 
250,000 
2.5 
u 
u 
u  u 
1 
250,000 
4.5 
(( 
u 
15 A      Pituitary  Extract 
u  u 
1 
250,000 
65  mm. 
contraction 
1 
250,000 
66 
a 
(( 
F.  E.  Cotton  R.  B.  (N.  F.) 
1 
1.000 
9 
u 
u 
Pituitary  Extract 
1 
300,000 
42.4 
u 
u 
F.  E.  Ergot 
1 
5,000 
70 
11 
u 
u 
1 
10,000 
64 
u 
u 
F.  E.  Cotton  R.  B.  (N.  F.) 
1 
1,000 
62 
ii 
u 
u 
1 
1,000 
40 
<( 
u 
u 
1 
1,000 
10 
« 
it 
F.  E.  Ergot 
1 
10,000 
17.5 
a 
u 
1 
:  10,000 
38.5 
u 
u 
F.  E.  Cotton  R.  B.  (N.  F.) 
1 
1,000 
30 
ii 
u 
*The  letters  indicate  the  corresponding  kymograms  on  Chart  2. 
Power  and  Browning,  cotton  root  bark  contains  no  tannin.^  The 
effect  of  the  alcohol,  however,  was  studied  by  applying  percentages 
equal  to  and  greater  than  that  found  in  the  solutions  of  cotton  root 
bark. 
Table  7  shows  the  results  of  fifteen  experiments  on  the  isolated 
guinea  pig's  uterus. 
