Am.  Jour.  Pharm. 
August,  1920. 
U.  5.  Pharmacopoeial  Revision. 
561 
and  300  Mils  of  distilled  water  to  saturate  the  powder  had  leave  a 
stratum  above.  Close  the  percolator  and  macerate  the  drug  for  two 
days.  Then  percolate  slowly,  using  the  remainder  of  the  mixture  and 
afterward  sufficient  distilled  water  to  yield  700  Mils  of  percolate. 
Dissolve  the  sugar  in  this  percolate  with  the  aid  of  the  heat  of  a  water 
bath,  strain  if  necessary,  and  finally  add  sufficient  distilled  water  to 
make  1000  mils. 
Syrupus  Senegae. — ^The  present  U.  S.  P.  product  is  unsatisfactory 
because  it  frequently  precipitates.  The  direct  addition  of  the  fluid- 
extract  to  syrup  naturally  causes  this  difficulty.  A  far  superior 
syrup,  pharmaceutically,  can  be  produced  by  the  process  suggested 
by  Beringer  (This  Journai^,  p.  320,  1909),  as  follows: 
Senega,  No.  20  powder   200  Gms. 
Mix  the  ammonia  water  and  glycerin  with  200  Mils  of  distilled 
water,  moisten  the  drug  with  sufficient  of  this  menstrum,  and  pack 
it  lightly  in  a  percolator.  Allow  the  moist  drug  to  macerate  for 
twenty-four  hours,  and  then  percolate  into  a  receiving  vessel,  grad- 
uated to  800  Mils,  and  containing  the  sugar ;  use  first  the  remainder 
of  the  menstrum  and  then  sufficient  water  to  make  the  sugar  and 
percolate  measure  800  Mils.  Reserve  this  portion  and  continue 
the  percolation  with  chloroform  water  until  the  drug  is  exhausted. 
Evaporate  this  second  percolate  to  200  Mils,  add  it  to  the  reserved 
portion,  agitate  until  the  sugar  is  dissolved,  strain  the  syrup,  and 
add  sufficient  water  to  make  the  product  measure  1000  Mils. 
Tinctura  Zingiheris. — It  has  been  shown  that  75  per  cent,  alcohol 
extracts  all  of  the  active  constituents  of  tincture  of  ginger.  The 
resulting  product  will  have  to  be  restandardized  from  the  standpoint 
of  maximum  and  minimum  extraction. 
Troches. — ^Troches  should  be  either  omitted  from  the  Pharma- 
copoeia or  modernized  as  to  flavor  and  size.  The  principle  of  making 
all  troches  i  Gm.  in  weight  has  proven  very  satisfactory  in  the  N.  F. 
The  cubeb  troche  is  probably  the  only  one  of  the  official  troches 
which  is  needed. 
Unguentum. — Yellow  wax  produces  a  better  product  than  white 
wax,  and  the  color  is  not  objectionable.  The  ointment  is  smoother 
and  seems  to  be  preserved  more  satisfactorily. 
Ammonia  Water  
Glycerin  
Sugar   
Water,  a  sufficient  quantity  to  make 
20  Mils 
100  Mils 
750  Gms. 
1000  Mils 
