MISCELLANY. 173 
[Sufficient care does not appear to have been here taken in testing for 
chromium. The metallic salts, it is known, are capable of forming 1 defi- 
nite compounds with animal and vegetable substances ; and in such cases 
their presence cannot be detected by the usual reagents. It is necessary 
to destroy all traces of organic matter before any reliance can be placed 
upon the indications afforded by the reagents.] 
Exp. iv. A dog, three months old, received 4 grains in half an ounce of 
water. In about half an hour vomiting ensued, and most of the solution 
was evacuated. The vomiting then ceased ; the dog remained for some 
time very weak, but eventually recovered. 
Fxp. v. Three grains in powder were given to a frog. (In the experi- 
ments with frogs they were placed in water, but not deep enough to cover 
the head.) Vomiting ensued immediately, and part of the undissolved 
salt was evacuated ; the vomiting, however, continued, and the animal 
died with convulsions in about an hour. The body was examined imme- 
diately ; there was no rigidity ; the brain and spinal cord were softened ; 
the lungs were dilated and traversed by red vessels; the heart was flabby. 
The intestinal canal was not much injected, and the contents of the 
stomach showed the presence of chromium. 
Exp. vi. A frog received 2 grains in pills. The consequences were 
similar to those of Exp. v. 
Exp. vii. Five grains were dissolved in 4 oz. of water, and a frog was 
placed in the solution. In a quarter of an hour it became restless for a 
short time ; in about an hour the restlessness returned, and continued to 
increase till, in about two hours, it attained its maximum. In eight hours 
spasms of the hind-feet came on with retching and vomiting. It died in 
about twelve hours, and the body was examined ten hours afterwards. 
It was very rigid ; the heart was flabby, and like the lungs gorged with 
blood. The brain and spinal cord were not examined. 
Exp. viii. A frog was placed in a solution containing 20 grains to 4 
oz. of water. The phenomena were similar to those observed in the 
preceding case, but more violent, and death ensued in three hours and a 
half. The brain and spinal cord were very soft ; the lungs small and 
dark colored, the heart filled with blood. The throat, stomach, and in- 
testines were highly injected. 
Exp. ix. A frog was placed in a solution containing 20 grains to 2 oz. 
of water. The results were similar to, but more violent than those of the 
two preceding cases. 
Exp. x. A frog was kept for forty-five minutes in a solution containing 
20 grains to 2 oz. of water. It was then taken out of the solution, washed, 
and placed in fresh water. The removal produced no change in the 
phenomena, and the animal died in four hours. 
Exp. xi. A solution of 10 grains in 3 drachms of water were injected 
into the jugular vein of a dog four months old. The animal cried violently 
