AmFeb.?i893arm*}  Gleanings  from  the  German  Journals.  71 
course  of  a  few  hours,  very  dangerous  symptoms  ;  the  presence  of  o- 1 
to  0-15  per  cent,  causing  death  quite  rapidly.  The  odor  of  H2S,  if 
present  to  the  extent  of  0-02  to  0-03  per  cent,  is  not  as  powerful  and 
unpleasant  as  if  present  in  smaller  quantity.  0  015  per  cent.  H2S  in 
the  air  can  be  inhaled  for  some  hours  without  detriment  ;  but  more 
than  0  02  per  cent,  produces  injurious  effects.  The  system  cannot 
be  made  to  tolerate  this  gas  ;  on  the  contrary,  it  becomes  more 
sensitive  upon  repeated  inhalations. — K.  B.  Lehmann  {Arch.  f. 
Hygien.),  Apotheker  Ztg.,  Repert.,  1892,  108. 
Tests  for  phenacetin,  methacetin  and  hydracetin. — Saturated,  aque- 
ous solutions  of  phenacetin  and  methacetin,  diluted  with  an  equal 
volume  of  chlorine  water,  upon  addition  of  a  few  drops  of  ammonia 
develop  a  red  or  brown  color ;  the  color  with  methacetin  develops 
quicker  and  is  more  intense  than  with  phenacetin.  The  addition  of 
5-10  per  cent,  quinine  sulphate  to  these  substances  produces  in 
the  test  a  beautiful  blue  color ;  the  test  succeeds  best  if  about  01 
of  the  mixture  be  agitated  with  5  cc.  water,  8-10  drops  chlorine 
water,  and  lastly,  2-3  drops  ammonia  water  be  added.  Hydrace- 
tin with  chlorine  water  gives  a  yellow  color,  intensified  by  the  addi- 
tion of  ammonia ;  in  the  presence  of  the  quinine  sulphate  a  fine  red 
color  results.  Other  substances  like  acetanilid  and  exalgin  them- 
selves give  no  coloration,  and  in  the  presence  of  quinine  sulphate 
give  only  the  green  color  due  to  the  latter  ;  morphine,  which  with 
chlorine  water  alone  or  with  ammonia,  gives  a  yellow  coloration  in 
the  presence  of  quinine  sulphate,  develops  only  a  green  color. — T. 
Gigli ;  Chemisclies  Rcpert.,  1892,  368. 
Tolypyrine. — This  derivative  of  antipyrine  is  />-tolyl  dimethylpyra- 
zolon,  and  differs  from  antipyrine  by  containing  an  additional 
methyl  group  introduced  into  the  phenyl  radical.  This  compound 
unites  with  salicylic  acid  just  as  does  antipyrine  (to  form  salipyrine) 
and  the  resulting  salt  is  commercially  called  tolysal ;  it  forms  color- 
less crystals  melting  at  101-1020  C,  difficultly  soluble  in  water, 
but  easily  soluble  in  alcohol. — Pharm.  Ztg.,  1892,  750  and  764. 
Cinchona  assay — As  an  improvement  upon  Haubensack's  method 
(Am.  Jour.  Pharm.,  1 891,  347)  which  by  Wegmuller  was  pronounced 
to  be  the  best  method  yet  proposed,  C.  Kursteiner  publishes  the 
following  and  invites  comparison  of  the  two  methods  :  20  grams 
cinchona  in  very  fine  powder  are  placed  in  a  flask  of  400-500  cc. 
