428 
Benzylidine  Dipiperidine. 
Am.  Jour.  Pharm. 
Sept.,  1893. 
and  in  part  of  a  nearly  colorless  crystalline  resin.  This  resin  gave 
no  characteristic  color  reactions  with  the  mineral  acids.  The 
ethereal  extract  from  the  bark  of  the  tree  did  not  impart  a  straw 
color  to  water,  and  gave  no  reactions  with  glucosidal  reagents. 
The  residue  in  this  case,  as  in  the  other,  consisted  of  oil  and  crystal- 
line resin. 
The  alcoholic  extracts  of  the  drugs  yielded  a  red-wine  color  to 
water,  which  color  was  in  part  removed  by  agitation  with  ether,  and 
on  evaporation  of  the  latter  solvent  there  were  deposited  orange 
crystals,  which  became  of  a  deep  violet  with  alkalies.  They  repre- 
sented the  juglandic  acid  of  former  investigators,  and  were  so  readily 
decomposed  that  mere  solution  in  ether  caused  their  decomposition 
with  the  formation  of  resinous  products,  insoluble  in  water.  The 
portion  of  the  alcoholic  extract  insoluble  in  water  consisted  of  this 
insoluble  residue.  A  qualitative  analysis  of  the  ash  confirmed,  in 
most  part,  Dawson's  report,  the  aluminum  was  not  found,  and  no 
doubt  the  former  investigators  were  misled  by  the  calcium  phos- 
phate. 
BENZYLIDINE  DIPIPERIDINE.1 
By  George  W.  Ascott. 
During  the  year  of  1891-92,  Chas.  F.  Tompkins  made  a  study 
of  benzylidine  dipiperidine  and  several  of  its  derivatives.  He 
showed  that  this  compound  could  be  readily  obtained  by  the  con- 
densation of  one  molecule  of  benzaldehyde  and  two  molecules  of 
piperidine.  The  readiness  with  which  this  reaction  takes  place  is 
quite  remarkable  and  would  appear  to  be  rather  incompatible  with 
the  decomposition  of  this  compound  into  its  components.  Of  the 
derivatives  of  benzylidine  dipiperidine  studied,  two  are  of  special 
interest.  One  of  these  was  prepared  by  Mr.  Tompkins,  by  passing 
hydrogen  sulphide  into  benzylidine  dipiperidine  in  alcoholic  solu- 
tion, when  it  separates  as  a  grayish  white  amorphous  powder,  which 
can  be  converted  into  a  crystalline  compound  with  comparative  ease. 
The  other  one,  a  crystalline  compound,  was  obtained  from  the 
mother  liquor  of  the  first.  Both  of  these  compounds  invite  further 
investigation. 
1  Read  before  the  meeting  of  the  Wis.  Pharm.  Assoc.,  Fond  du  Lac,  August, 
1893. 
