ON PHLORIDZINE. 
53 
sufficient to dissolve a great quantity of phloridzine. The 
author has endeavored to drive off this alkali by heat, in the 
hopes of forming a precipitate, but the liquid becomes colored 
without abandoning the phloridzine. 
Any acid precipates it by saturating the base.* 
Possessing a large quantity of phloridzine, M. Boullier has 
placed it in the hands of many practitioners, and its use has 
always been followed by the most happy success. Encouraged 
by such good results, he wished to extract it from the bark 
of the cherry tree root, in hopes to be able to offer it at the 
lowest price in commerce, but it was impossible to obtain the 
least trace of it, either by means of an aqueous decoc- 
tion, or by an alcoholic infusion; after thirty-six hours rest 
he found nothing, either on the bottom or sides of the vessel, 
but a very bitter resin. Meanwhile, notwithstanding the 
difficulty of procuring apple trees in full vigor, phloridzine 
will not be the less, says the author, employed hereafter by all 
the physicians; for its highly energetic properties, as well as 
its easy administration, will assure it the first rank among 
febrifuges. 
ADDITIONAL NOTE ON PHLORIDZINE. By T. Boullier. 
Since preparing the paper upon phloridzine, which I have sent 
to the Society of Medical Chemistry, I have applied myself anew 
to the extraction of this substance. Up to the present time, I 
have submitted the bark to two decoctions; the first of four, 
and the second of two hours only; but, convinced of the entire 
solubility of phloridzine in boiling water, I have thought 
so long a boiling was not necessary; that it was possible it 
* From these two last facts it would appear conclusive that phloridzine 
plays the part of an acid; at least, that it is not altered by the hydrated 
alkalies, as occurs in the case of daturine, hyosciamine, atrophine, 
and likewise in amydine. This will be a new object of research, 
which may lead to interesting results for science in general, and in par- 
ticular for the history of phloridzine. 
