292 
Varieties. 
(Am.  Jour.  Pharm. 
\       May,  1884. 
drug  is  continued  every  2 J  hours  at  least,  otherwise  shivering  occurs, 
and  the  temperature  rises  to  the  poiut  corresponding  to  the  acuteness 
of  the  disease;  this  drawback  is  overcome,  so  as  not  to  disturb  the 
night's  rest,  by  judicious  closing  during  the  day,  and  by  giving  a  full 
dose  of  2  grams  of  kairoline  the  last  thing  at  night.  The  action  of 
kairine  begins  25  minutes  after  the  dose  of  05  to  1  gram  is  taken  by 
the  mouth ;  the  fall  in  temperature  is  more  rapid  the  larger  the  dose, 
and  is  always  accompanied  by  profuse  sweating,  which  lasts  only  as 
long  as  the  temperature  continues  to  fall.  During  the  use  of  these 
drugs,  the  urine  becomes  green,  but  contains  no  sugar  or  albumin. 
Pneumonia  patients  especially  have  enjoyed  great  comfort  from  the 
use  of  this  drug ;  in  fact,  such  cases  can  be  kept  quite  free  of  fever.  It 
is  suggested  to  use  kairine  as  a  remedy  in  malarial  affections,  by  giving 
1  gram  hourly,  three  hours  before  the  expected  attacks. — Phar.  Jour, 
and  Trans.  [3],  14,  383,  384;  Jour.  Chem.  Soc,  April,  1884,  p.  474. 
;  ,   •    . j /-vr  ~  7~^~  ~ 
VARIETIES. 
Peptones  in  the  Urine  have  recently  ("Miss.  Val.  Med.  Monthly") 
received  considerable  attention  ;  some  observers  suppose  their  presence  is 
of  special  clinical  importance,  indicating  a  morbid  state  analogous  to,  or 
possibly  an  early  stage  of  granular  contracted  kidney.  The  elaborate  inves- 
tigation of  Dr.  R.  W.  Jabsch,  however,  tended  to  discredit  this  view.  He 
found  that  peptones  appeared  in  the  urine  with  great  frequency  in  cases 
where  there  was  a  considerable  amount  of  suppuration  from  whatever  cause, 
or  where  there  was  a  large  amount  of  exudation  ;  he  found  it  in  every  one 
of  twenty  cases  of  phthisis  with  purulent  expectoration,  and  of  five  cases 
of  epidemic  cerebro-spinal  meningitis,  and  twelve  cases  of  acute  rheuma- 
tism, as  well  as  in  twenty-four  out  of  twenty-nine  cases  of  croupous  pneu- 
monia. He  believes  that  the  peptonuria  is  due  to  the  re  absorption  of  the 
inflammatory  products,  and  does  not  depend  in  any  way  on  the  condition 
of  the  kidneys. —  Weekly  Med.  Review,  March  15,  1884. 
A  Caution  about  Jequirity. — After  reporting  a  case  of  sloughing  of 
the  cornea  after  the  use  of  jequirity,  in  the  "  Weekly  Medical  Review," 
February  23,  1884,  Dr.  S.  Pollak  formulates  as  follows  : 
1.  Jequirity  is  by  far  the  best  remedy  which  has  been  hitherto  used  for. 
trachoma  and  pannus. 
2.  It  does  all,  and  more  speedily,  that  has  ever  been  claimed  for  purulent 
inoculation,  minus  the  repulsiveness  of  the  last  remedy. 
3.  The  infusion  of  jequirity  must  be  used  only  when  perfectly  fresh. 
After  four  or  five  days  it  swarms  with  bacteria,  when  the  danger  of  their 
entering  the  tissue  and  causing  a  septic  state  is  very  great. 
