Am.  Jour.  Pharm. 
Oct.,  1884. 
Quinine  and  Homoquinine. 
515 
Calcium  and  Strontium  Chlorides. 
m.  p.  Solubility  at  0°.  40°. 
Calcium   28°  165*7  7,141-0 
Strontium   112°  106-2  205-8 
Information  is  yet  wanting  as  to  the  solubility  of  many  of  the  salts 
in  the  list. 
It  is  of  course  not  maintained  that  fusibility  is  the  sole  cause  of 
solubility,  for  amongst  the  commonest  phenomena  of  solution  are  very 
many  difficulties  which  cannot  be  explained  away.  But  there  can  be 
no  doubt  that  fusibility  and  solubility  are  closely  connected  together, 
and  I  have  ventured  to  bring  the  subject  under  the  notice  of  the 
Society  because  it  can  scarcely  be  advanced  any  further  till  a  much 
greater  store  of  experimental  data  has  been  accumulated. — Jour.  Chem. 
Soc,  July,  1884,  p.  266. 
QUININE  AND  HOMOQUININE.1  t 
By  O.  Hesse. 
I.  Quinine. 
The  question,  formerly  raised  repeatedly,  whether  quinine  occurs  in 
other  barks  than  those  of  the  genus  Cinchona,  I  was  able  to  answer  in 
the  affirmative  in  1871,  when  I  showed  that  a  bark  at  that  time  com- 
ing into  commerce  and  erroneously  sent  out  as  a  cinchona  bark, — the 
china  cuprea,  which  we  now  know  to  be  derived  from  Remijia 
pedunculata, — actually  contained  this  alkaloid.2  My  priority  in  this 
discovery  has  indeed  been  contested,  in  that  J.  E.  Howard  has  stated3 
that  already  in  1857  he  had  observed  this  bark  in  the  London  market 
and  found  it  to  contain  quinine,  although  he  had  published  nothing 
respecting  it.  But  since  Howard  only  a  short  time  previously  (Novem- 
ber, 1869,)  had  afresh  affirmed  to  the  quinologist  Wecldell4  the  ex- 
perimental law  at  that  time  generally  held  to  be  correct,  that  the 
cinchona  alkaloids  were  peculiar  to  the  cinchonas  only,  it  may  be  as- 
^rom  the  Annalen  der  Chemie,  ccxxv.,  95. 
2Berichte,  iv.,  818  ;  Am.  Jour.  Phar.,  1872,  213. 
3 Neues  Jahrbuch  f.  Pharm.,  xxxvi.,  296  ;  Fluckiger,  "  Die  Chinarinden," 
1883,  43. 
4  Uebersicht  d.  Cinchonen,  Weddell,  7. 
