A.m  Jour.  Pnarm. 
Dec,  1884. 
Brazilian  Drugs. 
627 
fevers,  especially  when  severe  (atuctische)  skin  eruptions  are  present. 
The  dose  of  the  powdered  bark  is  05  to  1  gram.  A  concentrated 
infusion  is  used  as  an  enema  in  prolapsus  ani. 
Casca  de  Pao  Pereira  (Geissospermum  Vellosii,  Fr.  Allen). — The 
active  principle,  geissospermine,  is  best  prepared  by  making  an 
alcoholic  extract,  distilling  off  the  alcohol  and  treating  the  residue  with 
acidulated  water  and  precipitating  with  ammonia.  When  prepared 
directly  from  a  watery  extract  of  the  bark,  the  alkaloid  is  purified 
with  difficulty. 
Casca  de  Sangue  de  Drago  (Croton  erythama,  Mart.  Euphorbiaceod). 
— The  bark  is  a  favorite  astringent.  A  decoction  of  the  fresh  bark 
evaporated  to  an  extract  of  a  weak  syrupy  consistence  is  known  as 
mellado  de  sangue  de  drago.  In  chronic  diarrhoea  of  adults  the  dose 
is  a  teaspoonful  three  times  a  day ;  for  children  a  teaspoonful  of  a 
mixture  of  2  grams  of  the  extract  with  60  grams  of  water  every  three 
hours.  It  is  employed  in  the  form  of  injection  for  gonorrhoea  and 
leucorrhoea.    It  has  also  been  used  as  a  vulnerary  with  success.1 
Casca  de  raiz  Timbo  (Lonchocarpus  Pecholtii,  Waura,  Leguminosai). 
— A  very  powerful  narcotic  drug,  which  deserves  to  be  introduced 
into  Europe. 
Casca  de  Tinguaciba  (Xanthoxylum  Tinguassiba,  St.  Hil.  Rutacece). 
— The  decoction  is  used  as  a  powerful  sudorific,  and  in  the  form  of  a 
gargle  for  affections  of  the  throat,  also  as  an  addition  to  odontalgic 
tincture.  Dr.  Peckolt  has  found  in  the  bark  an  alkaloid  producing 
effects  similar  to  those  of  pilocarpine. 
Quina  do  Remijio  (Remijia  ferruginea,  Ol.  Cinchonaceaz). — The 
root-bark  has  long  been  used  as  a  remedy  for  intermittent  fever  by  the 
wandering  natives.  The  active  principle  is  an  acid  resin  having  a 
shining  crystalline  appearance  and  named  by  Dr.  Peckolt  vieirin 
after  Dr.  J.  A.  Vieira  de  Mattos,  who  discovered  it  in  1860.  The 
vieirin  can  be  prepared  by  exhausting  the  powdered  bark  with  water 
rendered  alkaline  with  ammonium  or  sodium  hydrate  and  precipitating 
the  liquid  with  acetic  or  hydrochloric  acid.  If  extracted  by  means  of 
milk  of  lime  and  alcohol  it  is  obtained  in  a  shining  crystalline  form 
resembling  santonin.  It  is  soluble  in  alcohol  and  alkalies  and  is  given 
in  a  mixture  with  wine  and  bicarbonate  of  sodium. 
Raiz  de  azedinha  grama  (Oxalis  violacea,  Veil.). — Root  used  as  a 
diuretic  ;  it  is  sweet  and  edible. 
1  See  also  Archiv  der  Pharm.,  1862,  Bd.  108,  p.  142. 
