414 
GLEANINGS  PROM  GERMAN  JOURNALS. 
stirring  is  continued  until  a  perfectly  uniform  mixture  is  ob- 
tained. During  this  heating  and  stirring  there  is  always  an 
additional  loss  of  weight,  which  should  be  disregarded,  or  made 
up  with  a  little  alcohol,  according  to  the  consistence  of  the  ex- 
tract and  the  richness  of  the  Cinchona.  In  order  that  1  grain 
of  the  extract  should  represent  exactly  3  grains  of  the  powdered 
Cinchona,  the  total  extract  must  weigh  5J.  160  grs.  But  it  is 
quite  near  enough,  and  usually  makes  a  better  consistence  when 
the  extract  weighs  5§.  or  a  little  less.  With  the  quality  of  Cin- 
chonas used  by  the  writer,  and  the  Glycerin  of  full  officinal 
strength,  this  extract  when  hot  is  thin  enough  to  be  easily 
managed  and  transferred  to  pots  (the  inside  surfaces  of  which 
should  be  moistened  with  Glycerin)  with  facility,  and  when  cold 
is  firm  enough  to  be  rolled  into  pills  which  retain  their  form  for 
a  short  time  pretty  well,  even  in  warm  weather. 
(To  be  continued.) 
GLEANINGS  FROM  GERMAN  JOURNALS. 
By  J.  M.  Maisch. 
On  the  Quantity  of  Fibrin  separated  from  Blood.  Dr.  Sig- 
mund  Mayer  obtained  the  blood  from  the  carotis  of  a  dog 
through  a  forked  tube.  The  fibrin  was  washed  with  water,  ex- 
hausted with  boiling  alcohol,  dried  between  110°  and  120°  C, 
and  weighed.    The  results  of  his  experiments  are  as  follows  : — 
1.  Two  portions  of  the  same  blood,  treated  precisely  alike, 
may  yield  equal  or  different  quantities  of  fibrin. 
2.  These  irregularities  occur  whether  the  blood  coagulates 
quietly,  by  beating  or  shaking. 
3.  The  same  is  the  case,  whether  the  rapidity  of  coagulation 
is  increased  by  heating  in  a  water  bath  to  45°  C,  or  delayed  by 
immersing  in  ice. 
A  sufficient  explanation  of  this  behavior  cannot  be  given ;  it 
seems  to  support  the  hypothesis  of  Al.  Schmidt,  that  variable 
quantities  of  fibrino-plastic  matter,  of  which  blood  contains  an 
excess,  enters  into  the  formation  of  fibrin. 
The  author  corroborates  the  statements  of  others  regarding 
the  great  variations  in  the  amount  of  fibrin  yielded  by  the  blood 
of  different  individuals. 
