PHARMACY  OF  THE  CINCHONAS. 
517 
good  effect,  and  is  found  in  this  limited  use  to  be  a  convenient 
preparation,  though  not  adapted  quite  so  well  to  general  uses  as 
the  one  next  to  be  mentioned. 
JExtractum  Cinelioncti  Fluidum  Compositum — -Compound  Fluid 
Extract  of  Cinchona. 
Take  of  Cinchona,  either  Red  or  Yellow,  in  fine  powder,  six- 
teen troyounces. 
Glycerin,  eight  fluidounces,  or  nine  troyounces  and 
two  hundred  and  eighty  grains. 
Compound  Fluid  Extract  of  Bitter  Orange  Peel,  a 
sufficient  quantity. 
Alcohol,  six  pints  and  ten  fluidounces. 
Water,  a  sufficient  quantity. 
Mix  the  Cinchona  thoroughly  with  thirty  fluidounces  of  the 
Alcohol,  in  a  proper  vessel,  by  stirring  them  together  ;  cover  the 
vessel,  and  allow  the  mixture  to  stand  half  an  hour.  Then 
transfer  it  to  a  glass  funnel  prepared  for  percolation,  and  pour 
the  remainder  of  the  Alcohol  on  top,  as  required,  following  this 
with  water,  after  the  last  of  the  Alcohol  has  sunk  below  the  sur- 
face, until  the  percolate  becomes  cloudy,  and  makes  a  precipitate 
in  the  receiving  vessel.  Distil  off  the  Alcohol  from  the  perco- 
late by  means  of  a  water  bath,  and  stir  the  residue  on  the  bath 
until  it  weighs  five  troyounces.  To  this  add  the  Glycerin,  and 
warm  the  mixture  until  it  is  uniform.  Then  cool  it,  and  make 
it  up  to  the  measure  of  a  pint  with  Compound  Fluid  Extract  of 
Bitter  Orange  Peel,  and  agitate  the  whole  well  together.  The 
weight  of  the  pint  of  finished  fluid  extract  will  vary  somewhat 
with  the  temperature,  etc.,  but  should  be  about  8600  grains ; 
and  each  minim  represents  one  grain  of  the  Cinchona,  and  from 
one-third  to  a  quarter  of  a  grain  of  the  aromatics  in  half  a 
minim  of  Glycerin,  the  remainder  being  Alcohol  and  water. 
This  fluid  extract  resembles  the  last  in  color,  but  is  rather 
thicker,  and  has  the  fine  rich  odor  of  the  aromatics,  and  a  less 
pure  bitter  taste,  not  so  disagreeable  to  most  persons.  To 
many,  however,  both  are  agreeable,  and  almost  equally  so,  par- 
ticularly when  taken  in  wine.  The  solubility,  reactions,  dose 
and  mode  of  administration  are  the  same  as  in  the  simple  fluid 
extract. 
