92 
Pharmacological  Notes. 
f  Am.  Jour.  Pharm. 
1   February,  1899. 
consultation  by  Dr.  Coggeshall.  He  describes  her  condition  as 
follows : 
The  symptom  which  specially  attracted  our  attention  was  the 
extreme  degree  of  cyanosis.  This  was  one  of  a  peculiar  bluish 
tinge,  most  marked  in  the  fingers  and  lips.  Her  pulse  was  weak, 
but  otherwise  she  did  not  appear  so  ill  as  the  degree  of  cyanosis 
would  lead  one  to  expect. 
"  The  immediate  treatment,"  he  says,  "consisted  of  rest  and  aro- 
matic spirits  of  ammonia.  Under  these  her  strength  gradually 
returned." 
It  appears  that  the  patient  had  bought  a  packet  of  powders 
purporting  to  be  a  positive  cure  for  sick  and  nervous  headache. 
Analysis  showed  that  each  powder  contained  three  grains  of  ace- 
tanilide  and  two  grains  of  phenacetine,  with  a  little  caffeine.  She 
had  taken  five  of  the  powders  during  the  night,  and  had  thus 
ingested  in  all  fifteen  grains  of  acetanilide  and  ten  grains  of 
phenacetine. — New  York  Med.  your.,  November  5,  1898.    C.  B.  L. 
A  CURIOUS  CASE  OF  PHOSPHORUS  NECROSIS 
is  recorded  in  the  Lancet,  due  to  the  inhalation  of  phosphorus 
fumes.  The  patient  was  a  man  of  good  health,  consuming  about 
twenty  cigars  a  day,  and  using  many  matches  to  each  one,  as  he 
frequently  interrupted  the  smoking  during  his  work.  It  was  com- 
puted that  for  the  last  twenty  years  he  had  daily  inhaled  the  vapor 
given  off  by  over  100  matches.  The  progress  of  the  disease  in- 
volved the  loss  of  one  of  the  maxillae,  and  eventually  death  from 
exhaustion. — Philad.  Med.  Jour.,  December  10,  1898.      C.  B.  L. 
SUPRARENAL  EXTRACT. 
Von  Cyon  states  (Deutsche  Med.  Woch.,  from  Pfliigers  Archiv 
fiir  Phys.,  p.  370)  that  suprarenal  extract  has  a  highly  stimulating 
effect  on  the  sympathetic  nervous  system  of  the  heart  and  the  ves- 
sels (accelerants  and  vasomotors),  while  it  has  a  paralyzing  effect  upon 
the  regulator  nerves  of  these  organs,  the  vagus  and  depressor. — 
Journal  American  Medical  Association,  p.  1246.         J.  L.  D.  M. 
A  CASE  OF  SULPHONAL  POISONING. 
Richmond  [British  Medical  Journal,  October  29,  1898)  reports 
the  case  of  a  middle-aged  woman  to  whom  2  drams  of  sulphonal 
were  administered  accidentally.    The  patient  became  unconscious,. 
