2l6 
Investigation  into  "Hnsa" 
Am.  Jour.  Pharm. 
May,  1899. 
support  you  more  satisfactorily  without  the  heavy,  deadening 
effects,  and  you  will  be  better  able  to  attend  to  your  duties  than 
while  taking  opiates. 
"Sleep  all  you  can.  Undisturbed  sleep,  peaceful  rest,  is  the  best 
nerve  tonic ;  in  fact,  the  best  medicine ;  avoid  all  prescriptions  of 
proprietary  medicine,  etc.,  that  might  contain  opium  in  some 
form. 
"  If  these  directions  are  strictly  adhered  to,  if  you  totally  abstain 
from  opiates  during  treatment  and  otherwise  properly  take  the 
remedy,  you  will  be  absolutely  certain  of  an  easy,  permanent 
cure." 
The  vials  contained  liquids  of  one  uniform  brown*  red  color, 
such  as  burnt  sugar  imparts  to  water.  Preliminary  tests  made  on 
a  specimen  of  Husa  (No.  8),  obtained  previously,  had  demonstrated 
that  its  contents  were :  Morphine,  approximately,  1*3  per  cent.; 
salicylic  acid,  *i6  per  cent.;  alcohol,  12  per  cent.;  glycerine,  10  per 
cent.;  water,  q.  s.,  and  coloring  matter.  The  morphine  was  as  sul- 
phate. Systematic  assays  were  then  instituted  with  the  ten  vials 
to  determine  the  morphine  strength  of  the  various  liquids.  The 
result  is  as  follows : 
Twenty-five  c,c.  of  each  liquid  were  evaporated  to  about  5  c.c. 
and  then  brought  to  the  measure  of  10  c.c.  with  water.  To  the 
product  were  added  3  c.c.  of  alcohol ;  6  c.c.  of  ether  and  1  c.c.  of 
ammonia  (10  per  cent.).  The  mixture  was  shaken  frequently  until 
all  the  morphine  was  separated,  when  it  was  washed  and  weighed 
in  the  usual  manner  (U.S.P.  process). 
Result. — No.  1  contained  2-19  per  cent,  morphine  ;  No.  2,  1-98  per 
cent,  morphine;  No.  3,  1-95  percent,  morphine;  No. 4,  1-72  percent, 
morphine;  No.  5,  1-55  per  cent,  morphine;  No.  6,  1-46  per  cent, 
morphine;  No.  7,  1-59  per  cent,  morphine  ;  No.  8,  1-59  per  cent, 
morphine;  No.  9,  1*43  per  cent,  morphine;  No.  10,  1-33  per  cent, 
morphine. 
Accompanying  I  exhibit  in  separate  bottles,  the  morphine  ob- 
tained labeled  from  1  to  10  successively,  also  the  sulphuric  acid  as 
barium  sulphate  and  the  glycerine  and  salicylic  acid  from  the  pre- 
liminary examination.  It  will  be  observed  that  the  morphine  is  of 
a  pure  white,  a  condition  quite  different  from  morphine  obtained 
from  opium  by  the  assay  process,  for  then  it  has  a  yellowish  color. 
The  fact  that  it  is  so  pure  indicates,  also,  that  it  is  added  morphine, 
and  that  it  is  not  in  actual  combination.    The  morphine  obtained 
