Am.  Jour.  Pharm 
September,  1899. 
}    British  Pharmaceutical  Conference. 
451 
THE  DETERMINATION  OF  DIABETIC  GLUCOSE.   PICRIC  AND  FEH- 
LING'S  METHODS  COMPARED. 
By  R.  H.  Parker. 
A  comparison  of  the  picric  and  Fehling  methods  for  the  determination  of 
glucose  in  diabetic  urine  shows  that  the  advantages  of  the  latter  when 
dealing  with  high  percentages  may  be  realized  in  an  equal  degree  by  adding  a 
known  quantity  of  glucose  before  determination.  He  finds  that  the  produc- 
tion of  opacity  in  Fehling's  solution  by  alkalized  urine  is  characteristic  of 
glucose.  "Interfering  substances"  do  not  produce  that  opacity,  and  rarely 
occur  in  greater  quantity  than  a  picric  indication  of  C35  per  cent,  of  glucose. 
When  the  picric  indication  falls  below  04  per  cent.,  the  actual  amount  of  glu- 
cose present  may  be  approximately  ascertained  by  noting  the  point  at  which 
opacity  appears.  Finally,  samples  of  urine  giving  the  non-subsiding  yellow 
cuprous  oxide  may  be  rapidly  assayed  with  Fehling's  solution,  if  previously 
mixed  with  an  equal  volume  of  6  to  8  per  cent,  glucose  solution. 
ANALYTICAL  NOTES  ON  THE  B.P.  LOZENGES. 
By  Frederick  Davis. 
In  the  following  table  are  given  the  results  of  a  series  of  analyses  of  B.P. 
lozenges,  showing  the  quantity  of  active  principles  found  in  each  lozenge. 
It  will  be  observed  the  quantity  of  active  ingredient  is  very  nearly  that  which 
the  B.P.  directs,  and,  taking  into  consideration  experimental  error,  the  con- 
stants are  good  excepting  in  the  lozenges  of  sodium  bicarbonate  and  sulphur, 
and  in  these  cases  there  appears  to  be  a  laxity  in  making  which  should  not 
exist.  In  the  reduced  iron  lozenge  the  determination  was  calculated  upon  75 
per  cent,  basis  of  metallic  purity.  In  the  rhatany  and  cocaine  lozenge  the 
cocaine  hydrochloride  only  was  determined,  and  similarly  the  morphine  hy- 
drochloride in  the  morphine  and  ipecac  lozenges.  No  examination  of  the 
basis  has  been  made  in  any  case  : 
Sample. 
1    Benzoic  Acid. 
Carbolic  Acid. 
j    Tannic  Acid. 
3 
s 
w 
Catechu. 
3 
O. 
j>> 
*« 
0 
3 
w 
Reduced  Iron. 
Guaiacum. 
Ipecac. 
Krameria. 
Krameria  and 
Cocaine. 
Morphine. 
Morphine  and 
Ipecac 
Potassium 
Chlorate. 
Santonin. 
Sodium  Bicar- 
bonate. 
Sulphur. 
I  . 
II  . 
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ined. 
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a 
ned. 
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•049 
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•030 
029 
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5'9 
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termi 
termi 
I  "CO 
termi 
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i~. 
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a 
u 
V 
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„ 
3'i 
5'2 
IV  . 
•50 
1-08 
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2 '09 
<u 
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i'°5 
u 
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3'3 
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V  . 
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1-97 
Not 
Not 
i-oS 
Not 
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'042 
■027 
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VI  . 
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3 '03 
1*21 
3'9 
69 
HYDROGEN  PEROXIDE. 
By  Chas.  T.  Tyrer. 
The  author  has  endeavored  to  give  some  idea  of  the  rate  of  decomposition 
and  the  protective  value  of  various  agents  in  solutions  of  hydrogen  peroxide. 
