172 
Henchera  A  mericana. 
Am.  Jour.  Pharm. 
April,  1891. 
As  regards  the  method  of  administration  of  the  lymph,  a  letter  by 
Dr.  Libbertz  accompanies  it.  Mr.  Frank  X.  Moerk  has  kindly 
translated  it  as  follows  :  , 
DIRECTIONS  FOR  USING  1/YMPH. 
The  lymph  can  be  kept  for  a  long  time  without  decomposing.  The  dilutions, 
however,  speedily  spoil  and  become  turbid  ;  turbid  solutions  must  not  be  used. 
To  prevent  decomposition  of  the  dilutions  they  must  be  heated  to  boiling,  after 
each  opening  of  the  container.  Dilutions  made  with  phenol  solutions  do 
not  require  this  treatment.  * 
The  remedy  is  to  be  used  subcutaneously,  preferably  between  the  shoulder 
blades  or  the  hips.  The  injections  are  best  made  with  Koch's  syringe,  ster- 
ilized by  rinsing  with  absolute  alcohol ;  abscesses  by  this  procedure  are  posi- 
tively prevented.  In  using  an  ordinary  Pravaz's  syringe,  sterilize  it  as 
completely  as  possible  by  repeated  washing  with  absolute  alcohol ;  in  this 
case,  however,  abscesses  are  not  as  certainly  prevented. 
The  progress  of  the  body  temperature  must  be  observed  before  the  injection 
as  well  as  after  it.  It  is  necessary  to  take  the  temperature  every  three  hours 
for  at  least  one  day  before  the  injection,  and  to  provide  for  its  continuance 
during  the  course  of  treatment.  The  injections  should  be  made  in  the  early 
forenoon,  so  that  the  effect  on  the  temperature,  noticeable  after  a  few  hours, 
may  be  followed  the  same  day. 
For  the  first  injection  o-i  to  o'2  cc.  of  the  1  per  cent,  dilution  should  be 
used  ;  in  the  following  days  the  dose  is  carefully  increased  ;  if  fever  above 
38-5°  C.  (101-3°  F.)  follows,  the  dose  (previously  given?)  is  repeated  or  even 
omitted  ;  if  no  fever  or  a  slight  one  follows,  the  dose  may  be  increased  o*i  to 
0*2  cc.  of  the  1  per  cent,  dilution.  When  the  dose  has  reached  1  cc.  (1  per 
cent.)  oro'i  cc.  (10  per  cent.)  it  may,  with  proper  observation  of  the  tempera- 
ture, be  increased  from  o*i  to  0  2  cc.  of  the  ioper  cent,  dilution.  As  a  rule,  the 
daily  dose  should  not  exceed  1  cc.  of  the  10  per  cent,  dilution  ;  only  in  excep- 
tional cases  is  it  necessary  to  increase  to  2  cc.  of  that  dilution.  The  injections 
are  then  repeated  with  intervals  of  one  or  more  days  until  the  symptoms  dis- 
appear. 
In  the  treatment  of  lupus  (if  not  very  extensive)  adults  may  be  injected  at 
the  first  with  o'i  cc.  (10  per  cent.)  solution,  the  injection  to  be  repeated  when 
necessary.  This  is  also  the  case  in  articular,  bone  and  glandular  tubercu- 
losis. 
The  proper  comparison  of  the  lymph  can  only  be  guaranteed  if  the  lymph 
be  obtained  directly  from  the  undersigned. 
[signed]  Dr.  A.  Libbertz. 
HEUCHERA  AMERICANA,  LINNK 
By  Josiah  C.  Peacock. 
Contritution  from  the  Chemieal  Laboratory  of  trie  Philadelphia  College  of  Pharmacy. — 
No.  85. 
This  subject  was  taken  up  at  the  suggestion  of  Prof.  H.  Trimble, 
and  was  worked  under  his  instructions.  The  root  used  was  collected 
