19°  Gleanings  from  the  German  Journals.  {AmApr"?S^rm* 
less  than  015  per  cent,  resinous  matter,  indicating  that  these  mate- 
rials are  not  subjected  to  the  soap  and  acid  treatment.  Dr.  A. 
Link,  Phar.  Centralhalle,  1891,  10 1. 
Aseptic  Eye-water — Franke  recommends  adding  to  10  gm.  of 
solutions  of  cocaine  or  atropine  two  drops  of  a  one  per  cent,  solution 
of  mercuric  chloride  ;  this  will  keep  these  solutions  aseptic  for  years. 
—(Wiener  M.  Bl.)  Phar.  Centralhalle,  1891,  109. 
Soap-analysis — J.  Pinette  proposes  the  following  simple  method: 
2  grams  are  dissolved  in  boiling  neutral  alcohol,  any  residue  must 
be  further  examined.  To  the  solution  are  added  a  few  drops 
phenolphthalein  and,  in  case  an  alkaline  reaction  is  indicated, 
titrated  with  ?  sulphuric  acid  ;  the  neutralized  solution  is  diluted 
with  water  to  100  cc,  and  transferred  to  a  burette  holding  230  cc, 
and  graduated  in  0-5  cc.  to  200  cc,  after  cooling,  io  cc.  normal  sul- 
phuric acid  are  added  and  the  burette  filled  to  the  highest  mark 
with  a  mixture  of  equal  volumes  of  ether  and  petroleum-ether. 
The  stopper  is  inserted,  tied  down,  and  the  burette  gently  agitated 
until  the  fatty  acids  are  dissolved  ;  when  the  contents  have  com- 
pletely separated,  the  volume  of  each  layer  is  noted.  To  determine 
the  fatty  acids  25  cc.  of  the  ethereal  solution  is  removed  with  a 
pipette  evaporated,  dried  and  weighed.  To  determine  the  alkali  in 
combination  with  fatty  acids  25  cc.  of  the  acid  aqueous  solution  is 
removed  and  the  excess  of  sulphuric  acid  determined  by  titration 
with  sodium  hydrate. — (Chem.  Ztg.)  (Ztschr.  f.  Nahrungsm. 
(Inters,  u.  //.,)  1891,  27. 
Cantharidin  is  Professor  Liebreich's  remedv  for  tuberculosis, 
administered  by  hypodermic  injections.  The  solution  used  is  made 
as  follows:  o  2  gm.  cantharidin  and  0-4  gm.  potassium  hydrate 
(0-3  gm  sodium  hydrate)  are  warmed  with  20  cc.  water  in  a  water- 
bath  until  solution  is  effected  ;  this  solution  is  diluted  with  warm 
water, and  after* cooling  made  up  to  one  litre.  Cantharidin  C10H12O4 
is  the  anhydride  of  cantharidic  acid,  H2C10H12O5,  and  in  the  above 
solution  exists  as  cantharidate  of  potassium  (or  sodium)  C10H12K2O5. 
The  initial  dose  represents  01  mg.  cantharidin  which  is  gradually 
increased  to  0  6  mg.;  the  remedy  as  yet  has  only  been  used  in 
affections  of  the  larynx  and  is  easily  tolerated  by  the  system. 
Professor  Frankel,  upon  whose  patients  the  experiments  were  made, 
emphasizes  the  statement  that  the  bacilli  become  scarcer  and  thinner 
